Difference between revisions of "RXN0-1134"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=THR THR] == * smiles: ** CC(O)C([N+])C(=O)[O-] * inchi key: ** InChIKey=AYFVYJQAPQTCCC-GBXIJSLD...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN0-1134 RXN0-1134] == * direction: ** LEFT-TO-RIGHT * common name: ** pyruvate_dehydrogenase_e1_c...")
 
(2 intermediate revisions by the same user not shown)
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=THR THR] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN0-1134 RXN0-1134] ==
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* smiles:
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* direction:
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** CC(O)C([N+])C(=O)[O-]
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** LEFT-TO-RIGHT
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* inchi key:
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−
** InChIKey=AYFVYJQAPQTCCC-GBXIJSLDSA-N
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* common name:
 
* common name:
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** L-threonine
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** pyruvate_dehydrogenase_e1_component_subunit_alpha-_mitochondrial
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* molecular weight:
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** dihydrolipoamide_acetyltransferase
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** 119.12   
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** ORF
 +
* ec number:
 +
** [http://enzyme.expasy.org/EC/1.2.4.1 EC-1.2.4.1]
 
* Synonym(s):
 
* Synonym(s):
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** T
 
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** thr
 
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** thre
 
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** L-thr
 
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** threonine
 
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** 2-amino-3-hydroxybutyric acid
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[THREONINE--TRNA-LIGASE-RXN]]
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* With identifiers:
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* [[RME144]]
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** 1 [[PROTON]][c] '''+''' 1 [[PYRUVATE]][c] '''+''' 1 [[Pyruvate-dehydrogenase-lipoate]][c] '''=>''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[Pyruvate-dehydrogenase-acetylDHlipoyl]][c]
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* [[RXN-14249]]
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* With common name(s):
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* [[RXN-8626]]
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** 1 H+[c] '''+''' 1 pyruvate[c] '''+''' 1 a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] '''=>''' 1 CO2[c] '''+''' 1 a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine[c]
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* [[THREONINE-ALDOLASE-RXN]]
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* [[RXN-15122]]
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== Genes associated with this reaction  ==
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* [[THREODEHYD-RXN]]
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Genes have been associated with this reaction based on different elements listed below.
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* [[THREDEHYD-RXN]]
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* Gene: [[Tiso_gene_2693]]
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== Reaction(s) known to produce the compound ==
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** Source: [[annotation-in-silico_annotation]]
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* [[THRESYN-RXN]]
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*** Assignment: EC-NUMBER
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== Reaction(s) of unknown directionality ==
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** Source: [[annotation-experimental_annotation]]
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*** Assignment: EC-NUMBER
 +
* Gene: [[Tiso_gene_7519]]
 +
** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
 +
** Source: [[orthology-esiliculosus]]
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* Gene: [[Tiso_gene_6983]]
 +
** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Tiso_gene_17539]]
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-esiliculosus]]
 +
* Gene: [[Tiso_gene_2515]]
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-esiliculosus]]
 +
== Pathways  ==
 +
* [[PYRUVDEHYD-PWY]], pyruvate decarboxylation to acetyl CoA: [http://metacyc.org/META/NEW-IMAGE?object=PYRUVDEHYD-PWY PYRUVDEHYD-PWY]
 +
** '''3''' reactions found over '''3''' reactions in the full pathway
 +
== Reconstruction information  ==
 +
* Category: [[orthology]]
 +
** Source: [[orthology-esiliculosus]]
 +
*** Tool: [[pantograph]]
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* Category: [[manual]]
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** Source: [[manual-primary_network]]
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* Category: [[annotation]]
 +
** Source: [[annotation-in-silico_annotation]]
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*** Tool: [[pathwaytools]]
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** Source: [[annotation-experimental_annotation]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* CAS : 72-19-5
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* LIGAND-RXN:
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* METABOLIGHTS : MTBLC57926
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** [http://www.genome.jp/dbget-bin/www_bget?R01699 R01699]
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* PUBCHEM:
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* UNIPROT:
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=6971019 6971019]
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** [http://www.uniprot.org/uniprot/P06959 P06959]
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* HMDB : HMDB00167
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** [http://www.uniprot.org/uniprot/P26267 P26267]
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* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/P35485 P35485]
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** [http://www.genome.jp/dbget-bin/www_bget?C00188 C00188]
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** [http://www.uniprot.org/uniprot/Q59097 Q59097]
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* CHEBI:
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** [http://www.uniprot.org/uniprot/Q9N1X8 Q9N1X8]
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57926 57926]
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** [http://www.uniprot.org/uniprot/P45119 P45119]
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* BIGG : thr__L
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** [http://www.uniprot.org/uniprot/P11966 P11966]
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{{#set: smiles=CC(O)C([N+])C(=O)[O-]}}
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** [http://www.uniprot.org/uniprot/P35488 P35488]
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{{#set: inchi key=InChIKey=AYFVYJQAPQTCCC-GBXIJSLDSA-N}}
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** [http://www.uniprot.org/uniprot/P47515 P47515]
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{{#set: common name=L-threonine}}
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** [http://www.uniprot.org/uniprot/P21882 P21882]
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{{#set: molecular weight=119.12    }}
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** [http://www.uniprot.org/uniprot/P47516 P47516]
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{{#set: common name=T|thr|thre|L-thr|threonine|2-amino-3-hydroxybutyric acid}}
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** [http://www.uniprot.org/uniprot/P21881 P21881]
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{{#set: consumed by=THREONINE--TRNA-LIGASE-RXN|RME144|RXN-14249|RXN-8626|THREONINE-ALDOLASE-RXN|RXN-15122|THREODEHYD-RXN|THREDEHYD-RXN}}
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** [http://www.uniprot.org/uniprot/P21873 P21873]
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{{#set: produced by=THRESYN-RXN}}
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** [http://www.uniprot.org/uniprot/P16387 P16387]
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** [http://www.uniprot.org/uniprot/P0AFG8 P0AFG8]
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** [http://www.uniprot.org/uniprot/P08559 P08559]
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** [http://www.uniprot.org/uniprot/P11177 P11177]
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** [http://www.uniprot.org/uniprot/P29803 P29803]
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** [http://www.uniprot.org/uniprot/P29804 P29804]
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** [http://www.uniprot.org/uniprot/P26284 P26284]
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** [http://www.uniprot.org/uniprot/Q9JU08 Q9JU08]
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** [http://www.uniprot.org/uniprot/Q9CJD6 Q9CJD6]
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** [http://www.uniprot.org/uniprot/Q9JU07 Q9JU07]
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** [http://www.uniprot.org/uniprot/Q9CJD5 Q9CJD5]
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** [http://www.uniprot.org/uniprot/Q09171 Q09171]
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** [http://www.uniprot.org/uniprot/P52901 P52901]
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** [http://www.uniprot.org/uniprot/P79931 P79931]
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** [http://www.uniprot.org/uniprot/P79932 P79932]
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** [http://www.uniprot.org/uniprot/Q9D051 Q9D051]
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** [http://www.uniprot.org/uniprot/P10801 P10801]
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** [http://www.uniprot.org/uniprot/P21874 P21874]
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** [http://www.uniprot.org/uniprot/P49432 P49432]
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** [http://www.uniprot.org/uniprot/Q59820 Q59820]
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** [http://www.uniprot.org/uniprot/P35486 P35486]
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** [http://www.uniprot.org/uniprot/P35487 P35487]
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** [http://www.uniprot.org/uniprot/Q06437 Q06437]
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** [http://www.uniprot.org/uniprot/P32473 P32473]
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** [http://www.uniprot.org/uniprot/Q59107 Q59107]
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** [http://www.uniprot.org/uniprot/P73405 P73405]
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** [http://www.uniprot.org/uniprot/Q49109 Q49109]
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** [http://www.uniprot.org/uniprot/O48685 O48685]
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** [http://www.uniprot.org/uniprot/P52902 P52902]
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** [http://www.uniprot.org/uniprot/P52904 P52904]
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** [http://www.uniprot.org/uniprot/P52903 P52903]
 +
** [http://www.uniprot.org/uniprot/O66112 O66112]
 +
** [http://www.uniprot.org/uniprot/Q9Y8I5 Q9Y8I5]
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** [http://www.uniprot.org/uniprot/Q9Y8I6 Q9Y8I6]
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** [http://www.uniprot.org/uniprot/O69478 O69478]
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** [http://www.uniprot.org/uniprot/P10802 P10802]
 +
{{#set: direction=LEFT-TO-RIGHT}}
 +
{{#set: common name=pyruvate_dehydrogenase_e1_component_subunit_alpha-_mitochondrial}}
 +
{{#set: common name=dihydrolipoamide_acetyltransferase}}
 +
{{#set: common name=ORF}}
 +
{{#set: ec number=EC-1.2.4.1}}
 +
{{#set: gene associated=Tiso_gene_2693|Tiso_gene_7519|Tiso_gene_6983|Tiso_gene_17539|Tiso_gene_2515}}
 +
{{#set: in pathway=PYRUVDEHYD-PWY}}
 +
{{#set: reconstruction category=orthology|manual|annotation}}
 +
{{#set: reconstruction source=annotation-in-silico_annotation|manual-primary_network|annotation-experimental_annotation|orthology-esiliculosus}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:37, 21 March 2018

Reaction RXN0-1134

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • pyruvate_dehydrogenase_e1_component_subunit_alpha-_mitochondrial
    • dihydrolipoamide_acetyltransferase
    • ORF
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

Reconstruction information

External links






Retrieved from "http://gem-aureme.irisa.fr/tisogem/index.php?title=RXN0-1134&oldid=42752"