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| − | [[Category:Reaction]] | + | [[Category:Metabolite]] |
| − | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=Damaged-DNA-Pyrimidine Damaged-DNA-Pyrimidine] == |
| − | * direction: | + | * common name: |
| − | ** LEFT-TO-RIGHT | + | ** a damaged DNA pyrimidine |
| − | * ec number:
| + | |
| − | ** [http://enzyme.expasy.org/EC/4.1.3.4 EC-4.1.3.4]
| + | |
| | * Synonym(s): | | * Synonym(s): |
| | | | |
| − | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
| − | * With identifiers:
| + | * [[RXN0-2601]] |
| − | ** 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''=>''' 1 [[ACETYL-COA]][c] '''+''' 1 [[3-KETOBUTYRATE]][c]
| + | == Reaction(s) known to produce the compound == |
| − | * With common name(s):
| + | == Reaction(s) of unknown directionality == |
| − | ** 1 (S)-3-hydroxy-3-methylglutaryl-CoA[c] '''=>''' 1 acetyl-CoA[c] '''+''' 1 acetoacetate[c]
| + | |
| − | | + | |
| − | == Genes associated with this reaction == | + | |
| − | Genes have been associated with this reaction based on different elements listed below.
| + | |
| − | * [[Tiso_gene_3769]] | + | |
| − | ** [[pantograph]]-[[athaliana]]
| + | |
| − | ** [[pantograph]]-[[esiliculosus]]
| + | |
| − | == Pathways == | + | |
| − | * [[PWY66-367]], ketogenesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-367 PWY66-367]
| + | |
| − | ** '''5''' reactions found over '''5''' reactions in the full pathway
| + | |
| − | * [[LEU-DEG2-PWY]], L-leucine degradation I: [http://metacyc.org/META/NEW-IMAGE?object=LEU-DEG2-PWY LEU-DEG2-PWY]
| + | |
| − | ** '''6''' reactions found over '''6''' reactions in the full pathway
| + | |
| − | * [[PWY-5074]], mevalonate degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5074 PWY-5074]
| + | |
| − | ** '''1''' reactions found over '''2''' reactions in the full pathway
| + | |
| − | == Reconstruction information == | + | |
| − | * Category: [[orthology]]
| + | |
| − | ** Source: [[orthology-athaliana]]
| + | |
| − | *** Tool: [[pantograph]]
| + | |
| − | ** Source: [[orthology-esiliculosus]]
| + | |
| − | *** Tool: [[pantograph]]
| + | |
| − | * Category: [[annotation]]
| + | |
| − | ** Source: [[annotation-experimental_annotation]]
| + | |
| − | *** Tool: [[pathwaytools]]
| + | |
| − | ** Source: [[annotation-in-silico_annotation]]
| + | |
| − | *** Tool: [[pathwaytools]]
| + | |
| | == External links == | | == External links == |
| − | * RHEA:
| + | {{#set: common name=a damaged DNA pyrimidine}} |
| − | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=24404 24404]
| + | {{#set: consumed by=RXN0-2601}} |
| − | * LIGAND-RXN:
| + | |
| − | ** [http://www.genome.jp/dbget-bin/www_bget?R01360 R01360]
| + | |
| − | * UNIPROT:
| + | |
| − | ** [http://www.uniprot.org/uniprot/P35914 P35914]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P35915 P35915]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q8L7K2 Q8L7K2]
| + | |
| − | {{#set: direction=LEFT-TO-RIGHT}} | + | |
| − | {{#set: ec number=EC-4.1.3.4}} | + | |
| − | {{#set: gene associated=Tiso_gene_3769}}
| + | |
| − | {{#set: in pathway=PWY66-367|LEU-DEG2-PWY|PWY-5074}}
| + | |
| − | {{#set: reconstruction category=orthology|annotation}}
| + | |
| − | {{#set: reconstruction source=annotation-experimental_annotation|orthology-athaliana|annotation-in-silico_annotation|orthology-esiliculosus}}
| + | |
| − | {{#set: reconstruction tool=pantograph|pathwaytools}}
| + | |
