Difference between revisions of "3-HYDROXY-KYNURENINASE-RXN"

From metabolic_network
Jump to: navigation, search
(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=PAPS PAPS] == * smiles: ** C(OP(=O)([O-])OS(=O)(=O)[O-])C1(C(OP(=O)([O-])[O-])C(O)C(O1)N3(C=NC2...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-HYDROXY-KYNURENINASE-RXN 3-HYDROXY-KYNURENINASE-RXN] == * direction: ** LEFT-TO-RIGHT * common na...")
 
Line 1: Line 1:
−
[[Category:Metabolite]]
+
[[Category:Reaction]]
−
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=PAPS PAPS] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-HYDROXY-KYNURENINASE-RXN 3-HYDROXY-KYNURENINASE-RXN] ==
−
* smiles:
+
* direction:
−
** C(OP(=O)([O-])OS(=O)(=O)[O-])C1(C(OP(=O)([O-])[O-])C(O)C(O1)N3(C=NC2(C(N)=NC=NC=23)))
+
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
−
** 3'-phosphoadenylyl-sulfate
+
** kynureninase
−
* inchi key:
+
* ec number:
−
** InChIKey=GACDQMDRPRGCTN-KQYNXXCUSA-J
+
** [http://enzyme.expasy.org/EC/3.7.1.3 EC-3.7.1.3]
−
* molecular weight:
+
−
** 503.23   
+
 
* Synonym(s):
 
* Synonym(s):
−
** phosphoadenosine-5'-phosphosulfate
 
−
** PAPS
 
−
** phosphoadenosine phosphosulfate
 
−
** 3'-phosphoadenosine-5'-phosphosulfate
 
−
** 3'-phosphoadenylyl sulfate
 
−
** 3'-phospho-5'-adenylyl sulfate
 
  
−
== Reaction(s) known to consume the compound ==
+
== Reaction Formula ==
−
* [[RXN-18303]]
+
* With identifiers:
−
* [[RXN-18301]]
+
** 1 [[WATER]][c] '''+''' 1 [[3-HYDROXY-L-KYNURENINE]][c] '''=>''' 1 [[3-HYDROXY-ANTHRANILATE]][c] '''+''' 1 [[L-ALPHA-ALANINE]][c] '''+''' 1 [[PROTON]][c]
−
* [[RXN-10614]]
+
* With common name(s):
−
* [[RXN-10615]]
+
** 1 H2O[c] '''+''' 1 3-hydroxy-L-kynurenine[c] '''=>''' 1 3-hydroxyanthranilate[c] '''+''' 1 L-alanine[c] '''+''' 1 H+[c]
−
* [[RXN6666-9]]
+
 
−
* [[GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN]]
+
== Genes associated with this reaction  ==
−
* [[RXN-11059]]
+
Genes have been associated with this reaction based on different elements listed below.
−
* [[RXN-10777]]
+
* Gene: [[Tiso_gene_10685]]
−
* [[RXN-10782]]
+
** Source: [[annotation-in-silico_annotation]]
−
* [[RXN-11058]]
+
*** Assignment: EC-NUMBER
−
== Reaction(s) known to produce the compound ==
+
* Gene: [[Tiso_gene_10684]]
−
* [[AASP]]
+
** Source: [[annotation-in-silico_annotation]]
−
== Reaction(s) of unknown directionality ==
+
*** Assignment: EC-NUMBER
−
* [[PAPSPAPtm]]
+
== Pathways  ==
−
* [[PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN]]
+
* [[PWY-5651]], L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5651 PWY-5651]
−
* [[ADENYLYLSULFKIN-RXN]]
+
** '''4''' reactions found over '''5''' reactions in the full pathway
−
* [[ARYL-SULFOTRANSFERASE-RXN]]
+
* [[PWY-6309]], L-tryptophan degradation XI (mammalian, via kynurenine): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6309 PWY-6309]
−
* [[1.8.4.8-RXN]]
+
** '''9''' reactions found over '''17''' reactions in the full pathway
−
* [[RXN-15589]]
+
== Reconstruction information  ==
−
* [[RXN-15588]]
+
* Category: [[annotation]]
−
* [[RXN-17203]]
+
** Source: [[annotation-in-silico_annotation]]
−
* [[RXN-15587]]
+
*** Tool: [[pathwaytools]]
−
* [[R163-RXN]]
+
−
* [[PAPSPAPthr]]
+
 
== External links  ==
 
== External links  ==
−
* CAS : 482-67-7
+
* RHEA:
−
* BIGG : paps
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=25143 25143]
−
* PUBCHEM:
+
* LIGAND-RXN:
−
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=46926099 46926099]
+
** [http://www.genome.jp/dbget-bin/www_bget?R02668 R02668]
−
* KNAPSACK : C00007446
+
{{#set: direction=LEFT-TO-RIGHT}}
−
* HMDB : HMDB01134
+
{{#set: common name=kynureninase}}
−
* LIGAND-CPD:
+
{{#set: ec number=EC-3.7.1.3}}
−
** [http://www.genome.jp/dbget-bin/www_bget?C00053 C00053]
+
{{#set: gene associated=Tiso_gene_10685|Tiso_gene_10684}}
−
* CHEBI:
+
{{#set: in pathway=PWY-5651|PWY-6309}}
−
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=58339 58339]
+
{{#set: reconstruction category=annotation}}
−
* METABOLIGHTS : MTBLC58339
+
{{#set: reconstruction source=annotation-in-silico_annotation}}
−
{{#set: smiles=C(OP(=O)([O-])OS(=O)(=O)[O-])C1(C(OP(=O)([O-])[O-])C(O)C(O1)N3(C=NC2(C(N)=NC=NC=23)))}}
+
{{#set: reconstruction tool=pathwaytools}}
−
{{#set: common name=3'-phosphoadenylyl-sulfate}}
+
−
{{#set: inchi key=InChIKey=GACDQMDRPRGCTN-KQYNXXCUSA-J}}
+
−
{{#set: molecular weight=503.23    }}
+
−
{{#set: common name=phosphoadenosine-5'-phosphosulfate|PAPS|phosphoadenosine phosphosulfate|3'-phosphoadenosine-5'-phosphosulfate|3'-phosphoadenylyl sulfate|3'-phospho-5'-adenylyl sulfate}}
+
−
{{#set: consumed by=RXN-18303|RXN-18301|RXN-10614|RXN-10615|RXN6666-9|GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN|RXN-11059|RXN-10777|RXN-10782|RXN-11058}}
+
−
{{#set: produced by=AASP}}
+
−
{{#set: reversible reaction associated=PAPSPAPtm|PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN|ADENYLYLSULFKIN-RXN|ARYL-SULFOTRANSFERASE-RXN|1.8.4.8-RXN|RXN-15589|RXN-15588|RXN-17203|RXN-15587|R163-RXN|PAPSPAPthr}}
+

Latest revision as of 19:37, 21 March 2018

Reaction 3-HYDROXY-KYNURENINASE-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • kynureninase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-5651, L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde: PWY-5651
    • 4 reactions found over 5 reactions in the full pathway
  • PWY-6309, L-tryptophan degradation XI (mammalian, via kynurenine): PWY-6309
    • 9 reactions found over 17 reactions in the full pathway

Reconstruction information

External links





Retrieved from "http://gem-aureme.irisa.fr/tisogem/index.php?title=3-HYDROXY-KYNURENINASE-RXN&oldid=42787"