Difference between revisions of "3-HYDROXY-KYNURENINASE-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=PAPS PAPS] == * smiles: ** C(OP(=O)([O-])OS(=O)(=O)[O-])C1(C(OP(=O)([O-])[O-])C(O)C(O1)N3(C=NC2...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-HYDROXY-KYNURENINASE-RXN 3-HYDROXY-KYNURENINASE-RXN] == * direction: ** LEFT-TO-RIGHT * common na...")
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=PAPS PAPS] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-HYDROXY-KYNURENINASE-RXN 3-HYDROXY-KYNURENINASE-RXN] ==
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* smiles:
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* direction:
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** C(OP(=O)([O-])OS(=O)(=O)[O-])C1(C(OP(=O)([O-])[O-])C(O)C(O1)N3(C=NC2(C(N)=NC=NC=23)))
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** LEFT-TO-RIGHT
 
* common name:
 
* common name:
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** 3'-phosphoadenylyl-sulfate
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** kynureninase
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* inchi key:
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* ec number:
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** InChIKey=GACDQMDRPRGCTN-KQYNXXCUSA-J
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** [http://enzyme.expasy.org/EC/3.7.1.3 EC-3.7.1.3]
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* molecular weight:
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** 503.23   
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* Synonym(s):
 
* Synonym(s):
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** phosphoadenosine-5'-phosphosulfate
 
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** PAPS
 
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** phosphoadenosine phosphosulfate
 
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** 3'-phosphoadenosine-5'-phosphosulfate
 
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** 3'-phosphoadenylyl sulfate
 
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** 3'-phospho-5'-adenylyl sulfate
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[RXN-18303]]
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* With identifiers:
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* [[RXN-18301]]
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** 1 [[WATER]][c] '''+''' 1 [[3-HYDROXY-L-KYNURENINE]][c] '''=>''' 1 [[3-HYDROXY-ANTHRANILATE]][c] '''+''' 1 [[L-ALPHA-ALANINE]][c] '''+''' 1 [[PROTON]][c]
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* [[RXN-10614]]
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* With common name(s):
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* [[RXN-10615]]
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** 1 H2O[c] '''+''' 1 3-hydroxy-L-kynurenine[c] '''=>''' 1 3-hydroxyanthranilate[c] '''+''' 1 L-alanine[c] '''+''' 1 H+[c]
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* [[RXN6666-9]]
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* [[GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN]]
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== Genes associated with this reaction  ==
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* [[RXN-11059]]
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Genes have been associated with this reaction based on different elements listed below.
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* [[RXN-10777]]
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* Gene: [[Tiso_gene_10685]]
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* [[RXN-10782]]
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** Source: [[annotation-in-silico_annotation]]
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* [[RXN-11058]]
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*** Assignment: EC-NUMBER
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== Reaction(s) known to produce the compound ==
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* Gene: [[Tiso_gene_10684]]
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* [[AASP]]
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** Source: [[annotation-in-silico_annotation]]
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== Reaction(s) of unknown directionality ==
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*** Assignment: EC-NUMBER
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* [[PAPSPAPtm]]
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== Pathways  ==
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* [[PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN]]
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* [[PWY-5651]], L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5651 PWY-5651]
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* [[ADENYLYLSULFKIN-RXN]]
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** '''4''' reactions found over '''5''' reactions in the full pathway
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* [[ARYL-SULFOTRANSFERASE-RXN]]
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* [[PWY-6309]], L-tryptophan degradation XI (mammalian, via kynurenine): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6309 PWY-6309]
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* [[1.8.4.8-RXN]]
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** '''9''' reactions found over '''17''' reactions in the full pathway
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* [[RXN-15589]]
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== Reconstruction information  ==
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* [[RXN-15588]]
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* Category: [[annotation]]
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* [[RXN-17203]]
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** Source: [[annotation-in-silico_annotation]]
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* [[RXN-15587]]
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*** Tool: [[pathwaytools]]
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* [[R163-RXN]]
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* [[PAPSPAPthr]]
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== External links  ==
 
== External links  ==
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* CAS : 482-67-7
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* RHEA:
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* BIGG : paps
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=25143 25143]
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* PUBCHEM:
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* LIGAND-RXN:
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=46926099 46926099]
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** [http://www.genome.jp/dbget-bin/www_bget?R02668 R02668]
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* KNAPSACK : C00007446
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{{#set: direction=LEFT-TO-RIGHT}}
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* HMDB : HMDB01134
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{{#set: common name=kynureninase}}
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* LIGAND-CPD:
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{{#set: ec number=EC-3.7.1.3}}
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** [http://www.genome.jp/dbget-bin/www_bget?C00053 C00053]
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{{#set: gene associated=Tiso_gene_10685|Tiso_gene_10684}}
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* CHEBI:
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{{#set: in pathway=PWY-5651|PWY-6309}}
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=58339 58339]
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{{#set: reconstruction category=annotation}}
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* METABOLIGHTS : MTBLC58339
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{{#set: reconstruction source=annotation-in-silico_annotation}}
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{{#set: smiles=C(OP(=O)([O-])OS(=O)(=O)[O-])C1(C(OP(=O)([O-])[O-])C(O)C(O1)N3(C=NC2(C(N)=NC=NC=23)))}}
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{{#set: reconstruction tool=pathwaytools}}
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{{#set: common name=3'-phosphoadenylyl-sulfate}}
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{{#set: inchi key=InChIKey=GACDQMDRPRGCTN-KQYNXXCUSA-J}}
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{{#set: molecular weight=503.23    }}
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{{#set: common name=phosphoadenosine-5'-phosphosulfate|PAPS|phosphoadenosine phosphosulfate|3'-phosphoadenosine-5'-phosphosulfate|3'-phosphoadenylyl sulfate|3'-phospho-5'-adenylyl sulfate}}
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{{#set: consumed by=RXN-18303|RXN-18301|RXN-10614|RXN-10615|RXN6666-9|GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN|RXN-11059|RXN-10777|RXN-10782|RXN-11058}}
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{{#set: produced by=AASP}}
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{{#set: reversible reaction associated=PAPSPAPtm|PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN|ADENYLYLSULFKIN-RXN|ARYL-SULFOTRANSFERASE-RXN|1.8.4.8-RXN|RXN-15589|RXN-15588|RXN-17203|RXN-15587|R163-RXN|PAPSPAPthr}}
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Latest revision as of 20:37, 21 March 2018

Reaction 3-HYDROXY-KYNURENINASE-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • kynureninase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-5651, L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde: PWY-5651
    • 4 reactions found over 5 reactions in the full pathway
  • PWY-6309, L-tryptophan degradation XI (mammalian, via kynurenine): PWY-6309
    • 9 reactions found over 17 reactions in the full pathway

Reconstruction information

External links





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