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	Common name	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
1.5.1.20-RXN	Methylenetetrahydrofolate reductase -methylenetetrahydrofolate reductase	EC-1.5.1.20	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 16954 Tiso gene 14582	PWY-2201 1CMET2-PWY CODH-PWY PWY-3841
1.5.1.8-RXN		EC-1.5.1.8	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation	Tiso gene 1156	LYSINE-DEG1-PWY
1.5.1.9-RXN	Saccharopine dehydrogenase	EC-1.5.1.9	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9366 Tiso gene 7038 Tiso gene 7039 Tiso gene 4160 Tiso gene 10095 Tiso gene 1156	LYSINE-DEG1-PWY
1.6.4.4-RXN	Nucleoredoxin ORF	EC-1.8.1.8	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 475 Tiso gene 15704
1.8.4.12-RXN	Peptide methionine-r-sulfoxide reductase ORF Methionine sulfoxide reductase with associated domain Methionine sulfoxide reductase b	EC-1.8.4.12	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 16975 Tiso gene 6049 Tiso gene 18058 Tiso gene 14455 Tiso gene 19578
1.8.4.14-RXN	Peptide methionine-r-sulfoxide reductase	EC-1.8.4.14	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 19578
13-BETA-GLUCAN-SYNTHASE-RXN	-beta-glucan synthase component gls2 Callose synthase Callose Beta-glucan synthesis-associated	EC-2.4.1.34	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 7603 Tiso gene 5462 Tiso gene 7967 Tiso gene 7966 Tiso gene 3322 Tiso gene 5460	PWY-6773
14-LACTONASE-RXN	Gluconolactonase	EC-3.1.1.25	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 1948 Tiso gene 1947
1TRANSKETO-RXN	Transketolase	EC-2.2.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Orthology-athaliana Annotation-experimental annotation Orthology-synechocystis	Tiso gene 5008 Tiso gene 11559	P124-PWY CALVIN-PWY P21-PWY PWY-5723 PWY-1861 P185-PWY NONOXIPENT-PWY
2-AMINOADIPATE-AMINOTRANSFERASE-RXN		EC-2.6.1.39	Annotation	Pathwaytools	Annotation-in-silico annotation		PWY-3081 PWY-5283 LYSINE-AMINOAD-PWY LYSINE-DEG1-PWY PWY66-425
2-DEHYDROPANTOATE-REDUCT-RXN	2-dehydropantoate 2-reductase	EC-1.1.1.169	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-synechocystis	Tiso gene 16426 Tiso gene 10174 Tiso gene 12761 Tiso gene 10173 Tiso gene 12762 Tiso gene 9392	PANTO-PWY PWY-6654
2-HALOACID-DEHALOGENASE-RXN	Had family hydrolase	EC-3.8.1.10 EC-3.8.1.2	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 3200
2-ISOPROPYLMALATESYN-RXN	2-isopropylmalate synthase chloroplastic	EC-2.3.3.13	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 11453	LEUSYN-PWY PWY-6871
2-KETO-ADIPATE-DEHYDROG-RXN			Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation	Tiso gene 9330 Tiso gene 10209	PWY-5652 PWY66-425 LYSINE-DEG1-PWY
2-OCTAPRENYL-6-OHPHENOL-METHY-RXN	2-octaprenyl-6-hydroxyphenyl methylase 3-demethylubiquinone-9 3-methyltransferase	EC-2.1.1.222	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6943	PWY-6708
2.1.1.109-RXN	O-methyltransferase i	EC-2.1.1.109	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 20416	PWY-5956
2.1.1.127-RXN	Ribulose- bisphosphate carboxylase oxygenase large subunit n- chloropl	EC-2.1.1.127	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6151
2.1.1.137-RXN	ORF	EC-2.1.1.137	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 16361	PWY-4202
2.1.1.138-RXN	ORF	EC-2.1.1.137	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 16361	PWY-4202
2.1.1.143-RXN	Sterol methyltransferase	EC-2.1.1.143	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 11850 Tiso gene 11849	PWY-2541
2.1.1.63-RXN	Heat shock 40 kda protein Domain-containing protein	EC-2.1.1.63	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 12990 Tiso gene 12732
2.1.1.77-RXN	ORF L-isoaspartyl proteincarboxylmethyltransferase	EC-2.1.1.77	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 16936 Tiso gene 12221 Tiso gene 16935 Tiso gene 6376
2.3.1.118-RXN	Arylamine n-acetyltransferase	EC-2.3.1.118	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation	Tiso gene 9942
2.3.1.155-RXN		EC-2.3.1.155	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation		PWY-7654 PWY-7656
2.3.1.165-RXN	Polyketide synthase	EC-2.3.1.165	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 136 Tiso gene 13394 Tiso gene 10876 Tiso gene 500 Tiso gene 135	PWY-7490
2.3.1.168-RXN	3-methyl-2-oxobutanoate dehydrogenase	EC-2.3.1.168	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 11793 Tiso gene 3260	PWY-5046
2.3.1.179-RXN	3-oxoacyl-(acyl-carrier-protein) synthase ORF	EC-2.3.1.179	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation	Tiso gene 19302 Tiso gene 19303 Tiso gene 14485	PWY-5973
2.3.1.180-RXN	3-oxoacyl-(acyl-carrier-protein) synthase	EC-2.3.1.180	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 15991	PWY-4381
2.3.1.41-RXN	3-oxoacyl-synthase	EC-2.3.1.41	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9885 Tiso gene 15991 Tiso gene 19302 Tiso gene 5939 Tiso gene 13083 Tiso gene 14485
2.3.1.43-RXN	Phosphatidylcholine-sterol o-acyltransferase	EC-2.3.1.43	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 9096 Tiso gene 16209
2.3.1.97-RXN	Glycylpeptide n-tetradecanoyltransferase ORF	EC-2.3.1.97	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 8573 Tiso gene 17259 Tiso gene 11266
2.3.2.15-RXN	Phytochelatins synthase ORF	EC-2.3.2.15	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9670 Tiso gene 9671 Tiso gene 17830 Tiso gene 12647	PWY-6745
2.4.1.117-RXN	Udp-glucose--undecaprenyl-phosphate glucosyltransferase	EC-2.4.1.117	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 8160	MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
2.4.1.119-RXN	Oligosaccharyl transferase	EC-2.4.99.18	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 10448 Tiso gene 26	MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
2.4.1.125-RXN	Morn repeat protein	EC-2.4.1.5 EC-2.4.1.125	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 3363
2.4.1.135-RXN	ORF	EC-2.4.1.135	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 4139	PWY-6557
2.4.1.141-RXN		EC-2.4.1.141	Annotation	Pathwaytools	Annotation-in-silico annotation		MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
2.4.1.142-RXN	Chitobiosyldiphosphodolichol beta-	EC-2.4.1.142	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 8387	MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
2.4.1.224-RXN	Exostosin-1 Probable glycosyltransferase	EC-2.4.1.224	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6495 Tiso gene 6496	PWY-6558
2.4.1.225-RXN	Exostosin-1	EC-2.4.1.225	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6495	PWY-6558
2.4.1.232-RXN	Vacuolar protein sorting-associated protein 51 homolog ORF	EC-2.4.1.232	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10734 Tiso gene 16872
2.4.1.32-RXN	Family 2 glycosyl transferase	EC-2.4.1.32	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 322
2.4.1.46-RXN	Monogalactosyldiacylglycerol synthase	EC-2.4.1.46	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9530 Tiso gene 4096	PWY-401
2.4.1.83-RXN	Dolichol phosphate mannose	EC-2.4.1.83	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 16772	MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
2.4.2.12-RXN	Nicotinamide phosphoribosyltransferase	EC-2.4.2.12	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation	Tiso gene 8411 Tiso gene 8186 Tiso gene 8410	NAD-BIOSYNTHESIS-III
2.4.2.31-RXN	ORF Vacuolar protein 8 Ankyrin repeat domain protein Sir2-family protein hdac1	EC-2.4.2.31	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 1416 Tiso gene 16539 Tiso gene 17880 Tiso gene 18844 Tiso gene 19256 Tiso gene 16775 Tiso gene 17938 Tiso gene 14179 Tiso gene 16690 Tiso gene 8768 Tiso gene 19047 Tiso gene 16538 Tiso gene 13548 Tiso gene 18843 Tiso gene 5361 Tiso gene 1521
2.5.1.19-RXN	Pentafunctional protein	EC-2.5.1.19	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Manual-primary network Annotation-in-silico annotation Orthology-athaliana	Tiso gene 5752 Tiso gene 5753	PWY-6163
2.5.1.64-RXN	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase Protein chloroplastic	EC-2.2.1.9	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1922 Tiso gene 17551	PWY-5837
2.6.1.22-RXN		EC-2.6.1.22	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation		VALDEG-PWY
2.7.1.127-RXN	ORF Inositol -trisphosphate 3-kinase	EC-2.7.1.127	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 15142 Tiso gene 8121 Tiso gene 15143	PWY-6364 PWY-6362 PWY-6361

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