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	Common name	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
2.7.7.8-RXN	Polynucleotide phosphorylase polyadenylase	EC-2.7.7.8	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 2987
2.7.8.11-RXN		EC-2.7.8.11	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 6541	PHOSLIPSYN2-PWY PWY-7625 PWY-6351 PWY-6352
2.7.8.15-RXN		EC-2.7.8.15	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1604	MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
2.7.9.3-RXN	Selenophosphate synthetase	EC-2.7.9.3	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 5668 Tiso gene 5669 Tiso gene 14608	PWY0-901 PWY-6281
2.8.1.6-RXN	Biotin synthase	EC-2.8.1.6	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 10345	PWY0-1507 PWY-7380
2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN	4-methyl-2-oxopentanoate dehydrogenase (acylating)	EC-1.2.1	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation		LEU-DEG2-PWY
2OXOGLUTDECARB-RXN	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase mitochondrial Oxoglutarate decarboxylase 2-oxoglutarate decarboxylation	EC-1.2.4.2	Manual Annotation	Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation	Tiso gene 10209	PWY66-398 PWY-5084
2PGADEHYDRAT-RXN	Bifunctional enolase2transcriptionalactivator Bifunctional enolase 2 transcriptional activator Enolase 1	EC-4.2.1.11	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 5619 Tiso gene 13317 Tiso gene 14718 Tiso gene 8720	PWY-1042 P341-PWY PWY-2221 PWY-7124 PWY-1622 GLUCONEO-PWY GLYCOLYSIS NPGLUCAT-PWY ANAGLYCOLYSIS-PWY PWY-7218 PWY-6901 P124-PWY PWY-6886 PWY-5723 PWY-6142 P122-PWY PWY66-399 PWY-5484 PWY-7003
2TRANSKETO-RXN	Transketolase	EC-2.2.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Manual-primary network	Tiso gene 11559 Tiso gene 5008	PWY-6901 CALVIN-PWY P21-PWY PWY-5723 PWY-1861 P185-PWY NONOXIPENT-PWY
3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN	Ketopantoate hydroxymethyltransferase	EC-2.1.2.11	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 14465 Tiso gene 14466	PANTO-PWY
3-DEHYDROQUINATE-DEHYDRATASE-RXN	Pentafunctional protein	EC-4.2.1.10	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 5619 Tiso gene 14718 Tiso gene 8720 Tiso gene 5753 Tiso gene 5752	PWY-6163 PWY-6416 QUINATEDEG-PWY PWY-6707
3-DEHYDROQUINATE-SYNTHASE-RXN	3-dehydroquinate synthase Pentafunctional protein	EC-4.2.3.4	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 5753 Tiso gene 3446 Tiso gene 3445 Tiso gene 3974 Tiso gene 5752 Tiso gene 3447	PWY-6164
3-DEHYDROSPHINGANINE-REDUCTASE-RXN	3-ketodihydrosphingosine reductase	EC-1.1.1.102	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation	Tiso gene 18518	PWY-5129 PWY3DJ-12 SPHINGOLIPID-SYN-PWY
3-HYDROXY-KYNURENINASE-RXN	Kynureninase	EC-3.7.1.3	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10684 Tiso gene 10685	PWY-5651 PWY-6309
3-HYDROXYDECANOYL-ACP-DEHYDR-RXN	Polyketide synthase	EC-2.3.1.86 EC-2.3.1.85 EC-4.2.1.59	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 136 Tiso gene 500 Tiso gene 6884 Tiso gene 135 Tiso gene 10876 Tiso gene 13394	FASYN-ELONG-PWY
3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN	3-hydroxyisobutyrate mitochondrial 3-hydroxyisobutyrate dehydrogenase Uncharacterized oxidoreductase	EC-1.1.1.31	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus Annotation-experimental annotation	Tiso gene 19590 Tiso gene 5857 Tiso gene 19771 Tiso gene 7107 Tiso gene 19772 Tiso gene 19592	VALDEG-PWY
3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN	Enoyl- hydratase	EC-3.1.2.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-creinhardtii Annotation-experimental annotation	Tiso gene 2224	VALDEG-PWY
3-ISOPROPYLMALDEHYDROG-RXN	3-isopropylmalate dehydrogenase Β-isopropylmalic enzyme Threo-Ds-3-isopropylmalate dehydrogenase		Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-experimental annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 2920	LEUSYN-PWY PWY-6871
3-ISOPROPYLMALISOM-RXN	3-isopropylmalate dehydratase ORF (2R,3S)-3-isopropylmalate hydro-lyase Β-isopropylmalate dehydratase Α-isopropylmalate isomerase 3-isopropylmalate hydro-lyase		Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 12778	LEUSYN-PWY PWY-6871
3-OXOACID-COA-TRANSFERASE-RXN	Succinyl- :3-ketoacid-coenzyme a transferase mitochondrial	EC-2.8.3.5	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 6754

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