Semantic search

	Common name	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
2.7.7.8-RXN	Polynucleotide phosphorylase polyadenylase	EC-2.7.7.8	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 2987
2.7.8.11-RXN		EC-2.7.8.11	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 6541	PHOSLIPSYN2-PWY PWY-7625 PWY-6351 PWY-6352
2.7.8.15-RXN		EC-2.7.8.15	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1604	MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
2.7.9.3-RXN	Selenophosphate synthetase	EC-2.7.9.3	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 5668 Tiso gene 5669 Tiso gene 14608	PWY0-901 PWY-6281
2.8.1.6-RXN	Biotin synthase	EC-2.8.1.6	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 10345	PWY0-1507 PWY-7380
2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN	4-methyl-2-oxopentanoate dehydrogenase (acylating)	EC-1.2.1	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation		LEU-DEG2-PWY
2OXOGLUTDECARB-RXN	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase mitochondrial Oxoglutarate decarboxylase 2-oxoglutarate decarboxylation	EC-1.2.4.2	Manual Annotation	Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation	Tiso gene 10209	PWY66-398 PWY-5084
2PGADEHYDRAT-RXN	Bifunctional enolase2transcriptionalactivator Bifunctional enolase 2 transcriptional activator Enolase 1	EC-4.2.1.11	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 5619 Tiso gene 13317 Tiso gene 14718 Tiso gene 8720	PWY-1042 P341-PWY PWY-2221 PWY-7124 PWY-1622 GLUCONEO-PWY GLYCOLYSIS NPGLUCAT-PWY ANAGLYCOLYSIS-PWY PWY-7218 PWY-6901 P124-PWY PWY-6886 PWY-5723 PWY-6142 P122-PWY PWY66-399 PWY-5484 PWY-7003
2TRANSKETO-RXN	Transketolase	EC-2.2.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Manual-primary network	Tiso gene 11559 Tiso gene 5008	PWY-6901 CALVIN-PWY P21-PWY PWY-5723 PWY-1861 P185-PWY NONOXIPENT-PWY
3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN	Ketopantoate hydroxymethyltransferase	EC-2.1.2.11	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 14465 Tiso gene 14466	PANTO-PWY
3-DEHYDROQUINATE-DEHYDRATASE-RXN	Pentafunctional protein	EC-4.2.1.10	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 5619 Tiso gene 14718 Tiso gene 8720 Tiso gene 5753 Tiso gene 5752	PWY-6163 PWY-6416 QUINATEDEG-PWY PWY-6707
3-DEHYDROQUINATE-SYNTHASE-RXN	3-dehydroquinate synthase Pentafunctional protein	EC-4.2.3.4	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 5753 Tiso gene 3446 Tiso gene 3445 Tiso gene 3974 Tiso gene 5752 Tiso gene 3447	PWY-6164
3-DEHYDROSPHINGANINE-REDUCTASE-RXN	3-ketodihydrosphingosine reductase	EC-1.1.1.102	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation	Tiso gene 18518	PWY-5129 PWY3DJ-12 SPHINGOLIPID-SYN-PWY
3-HYDROXY-KYNURENINASE-RXN	Kynureninase	EC-3.7.1.3	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10684 Tiso gene 10685	PWY-5651 PWY-6309
3-HYDROXYDECANOYL-ACP-DEHYDR-RXN	Polyketide synthase	EC-2.3.1.86 EC-2.3.1.85 EC-4.2.1.59	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 136 Tiso gene 500 Tiso gene 6884 Tiso gene 135 Tiso gene 10876 Tiso gene 13394	FASYN-ELONG-PWY
3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN	3-hydroxyisobutyrate mitochondrial 3-hydroxyisobutyrate dehydrogenase Uncharacterized oxidoreductase	EC-1.1.1.31	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus Annotation-experimental annotation	Tiso gene 19590 Tiso gene 5857 Tiso gene 19771 Tiso gene 7107 Tiso gene 19772 Tiso gene 19592	VALDEG-PWY
3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN	Enoyl- hydratase	EC-3.1.2.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-creinhardtii Annotation-experimental annotation	Tiso gene 2224	VALDEG-PWY
3-ISOPROPYLMALDEHYDROG-RXN	3-isopropylmalate dehydrogenase Β-isopropylmalic enzyme Threo-Ds-3-isopropylmalate dehydrogenase		Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-experimental annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 2920	LEUSYN-PWY PWY-6871
3-ISOPROPYLMALISOM-RXN	3-isopropylmalate dehydratase ORF (2R,3S)-3-isopropylmalate hydro-lyase Β-isopropylmalate dehydratase Α-isopropylmalate isomerase 3-isopropylmalate hydro-lyase		Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 12778	LEUSYN-PWY PWY-6871
3-OXOACID-COA-TRANSFERASE-RXN	Succinyl- :3-ketoacid-coenzyme a transferase mitochondrial	EC-2.8.3.5	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 6754
3-OXOACYL-ACP-REDUCT-RXN	Polyketide synthase 3-oxoacyl-(acyl-carrier-protein)	EC-2.3.1.86 EC-2.3.1.85 EC-1.1.1.100	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 10876 Tiso gene 13394 Tiso gene 9885 Tiso gene 135 Tiso gene 13083 Tiso gene 136 Tiso gene 500	FASYN-ELONG-PWY
3-OXOACYL-ACP-SYNTH-BASE-RXN	3-oxoacyl-synthase Polyketide synthase	EC-2.3.1.86 EC-2.3.1.85 EC-2.3.1.41	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 19302 Tiso gene 136 Tiso gene 14485 Tiso gene 13394 Tiso gene 5939 Tiso gene 135 Tiso gene 10876 Tiso gene 500 Tiso gene 15991	PWY-5965 PWY-5966 FASYN-INITIAL-PWY PWY-7388
3-OXOACYL-ACP-SYNTH-RXN	Polyketide synthase 3-oxoacyl-synthase	EC-2.3.1.86 EC-2.3.1.85 EC-2.3.1.41	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 136 Tiso gene 15991 Tiso gene 14485 Tiso gene 135 Tiso gene 13394 Tiso gene 500 Tiso gene 5939 Tiso gene 10876 Tiso gene 19302	FASYN-ELONG-PWY
3-OXOADIPATE-ENOL-LACTONASE-RXN	Alpha beta hydrolase fold protein	EC-3.1.1.24	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10066	PROTOCATECHUATE-ORTHO-CLEAVAGE-PWY CATECHOL-ORTHO-CLEAVAGE-PWY
3.1.1.23-RXN	Lysophospholipase	EC-3.1.1.23	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 12375	LIPAS-PWY
3.1.1.47-RXN	Platelet-activating factor acetylhydrolase	EC-3.1.1.47	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 1774 Tiso gene 19650 Tiso gene 7990
3.1.1.64-RXN	All-trans-retinyl-palmitate hydrolase ORF Alpha beta hydrolase fold protein Alpha beta hydrolase Serine esterase Sialate o-acetylesterase-like protein Lysophospholipase Protein chloroplastic Para-nitrobenzyl esterase	EC-3.1.1.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1538 Tiso gene 1537 Tiso gene 9429 Tiso gene 1922 Tiso gene 2556 Tiso gene 19778 Tiso gene 12686 Tiso gene 4606 Tiso gene 4650 Tiso gene 10066 Tiso gene 17029 Tiso gene 16518 Tiso gene 11351
3.1.13.1-RXN	Exosome complex exonuclease Ribonuclease II	EC-3.1.13.1	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 11613 Tiso gene 11612
3.1.13.4-RXN	Nocturin	EC-3.1.13.4	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 17498 Tiso gene 17499 Tiso gene 17497
3.1.2.22-RXN	Palmitoyl-protein thioesterase 1	EC-3.1.2.22	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 12483
3.1.22.4-RXN	Structure-specific endonuclease subunit slx1 homolog	EC-3.1.22.4	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 11797
3.1.26.3-RXN	Low quality protein: ribonuclease 3-like Mini-ribonuclease 3 ORF	EC-3.1.26.3	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10649 Tiso gene 10131 Tiso gene 10752 Tiso gene 6282 Tiso gene 10753 Tiso gene 608
3.1.26.4-RXN	Ribonuclease ORF	EC-3.1.26.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9453 Tiso gene 3410 Tiso gene 9459 Tiso gene 16584 Tiso gene 10743
3.1.26.5-RXN	Oxidoreductase ORF	EC-3.1.26.5	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 14345 Tiso gene 14344 Tiso gene 10972 Tiso gene 3898 Tiso gene 10971	PWY0-1479
3.1.27.1-RXN	Uncharacterized protein ORF	EC-3.1.27.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 11979 Tiso gene 13100 Tiso gene 8896
3.1.27.9-RXN	ORF Trna intron catalytic cterminal subfamily protein	EC-4.6.1.16	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 3776 Tiso gene 5254 Tiso gene 10338	PWY-6689 PWY-7803
3.1.3.16-RXN	Formin domain containing protein Formin-like protein 14 Protein phosphatase 1 ORF Serine threonine-protein phosphatase Serine threonine protein phosphatase 2a Serine threonine-phosphatase Protein phosphatase Dual specificity phosphatase Protein phosphatase 2c	EC-3.1.3.16	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 452 Tiso gene 2190 Tiso gene 7036 Tiso gene 3751 Tiso gene 15176 Tiso gene 17314 Tiso gene 5305 Tiso gene 1395 Tiso gene 10912 Tiso gene 7035 Tiso gene 2578 Tiso gene 15559 Tiso gene 13371 Tiso gene 18472 Tiso gene 19603 Tiso gene 16524 Tiso gene 15788 Tiso gene 16525 Tiso gene 20309 Tiso gene 4137 Tiso gene 12379 Tiso gene 4164 Tiso gene 2034 Tiso gene 11870 Tiso gene 453 Tiso gene 18502 Tiso gene 12989 Tiso gene 1840
3.1.3.46-RXN		EC-3.1.3.46	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 15398 Tiso gene 2100 Tiso gene 893 Tiso gene 892	PWY66-423
3.1.3.56-RXN	Inositol polyphosphate 5phosphatase	EC-3.1.3.56	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6030	PWY-6363
3.1.3.57-RXN		EC-3.1.3.57	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation	Tiso gene 12601	PWY-6363
3.1.3.62-RXN		EC-3.1.3.62	Annotation	Pathwaytools	Annotation-in-silico annotation		PWY-6364
3.1.3.66-RXN	Type i inositol- -bisphosphate -4 Inositol3	EC-3.1.3.66	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 4823 Tiso gene 3052 Tiso gene 4822	PWY-6368
3.1.4.1-RXN	Alkaline phosphatase d Alkaline phosphatase	EC-3.1.4.1	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 9372 Tiso gene 3271
3.1.4.11-RXN	Phospholipase c beta 4 1-phosphatidylinositol- -bisphosphate phosphodiesterase gamma-2	EC-3.1.4.11	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 7561 Tiso gene 12020 Tiso gene 12019	PWY-6367 PWY-6351 PWY-7039 LIPASYN-PWY
3.1.4.17-RXN	Iesterase family member Amino acid transporter	EC-3.1.4.17	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9644 Tiso gene 1763 Tiso gene 12792
3.1.6.12-RXN	Arylsulfatase b	EC-3.1.6.12	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 15619
3.1.6.13-RXN	Iduronate-2-sulfatase	EC-3.1.6.13	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 18595
3.1.6.14-RXN	N-acetylglucosamine-6-sulfatase	EC-3.1.6.14	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 18170
3.2.1.106-RXN	Mannosyl-oligosaccharide glucosidase	EC-3.2.1.106	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 12662
3.2.1.113-RXN	Probable alpha-mannosidase i mns5 Mannosyl-oligosaccharide -alpha-mannosidase mns2 Class member 1	EC-3.2.1.113	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 4788 Tiso gene 11681 Tiso gene 2719
3.2.1.14-RXN	Glycoside hydrolase family 18 protein	EC-3.2.1.14	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10265	PWY-7822 PWY-6902 PWY-6855
3.2.1.143-RXN	Poly(adp-ribose) glycohydrolase-like	EC-3.2.1.143	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 16195
3.2.1.152-RXN	Endo- -beta-mannosidase	EC-3.2.1.152	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 17158 Tiso gene 5241 Tiso gene 15472
3.2.1.18-RXN	Sialidase Neuramidase	EC-3.2.1.18	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 18808 Tiso gene 18807 Tiso gene 17758 Tiso gene 17759 Tiso gene 9616
3.2.1.21-RXN	Beta-glucosidase-like chloroplastic ORF Low quality protein: beta-glucosidase-like chloroplastic-like Beta glucosidase	EC-3.2.1.21	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 6187 Tiso gene 15066 Tiso gene 3467 Tiso gene 8669 Tiso gene 5836 Tiso gene 6188 Tiso gene 2843 Tiso gene 15067 Tiso gene 6497 Tiso gene 13305 Tiso gene 13306 Tiso gene 6007 Tiso gene 10001 Tiso gene 2344
3.2.1.23-RXN	Polyprotein Glycoside hydrolase	EC-3.2.1.23	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1398 Tiso gene 17558 Tiso gene 12839
3.2.1.25-RXN	Mannosidase	EC-3.2.1.25	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 634
3.2.1.37-RXN	Beta-xylosidase/alpha-L-arabinofuranosidase	EC-3.2.1.37	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 10897
3.2.1.48-RXN	Sphingomyelinase	EC-3.2.1.26 EC-3.2.1.48	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 12644	PWY-621 PWY66-373
3.2.1.52-RXN	Beta-hexosaminidase	EC-3.2.1.52	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 14122 Tiso gene 1129
3.2.1.55-RXN	ORF Acetyl- carboxylase	EC-3.2.1.55	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 14849 Tiso gene 6300 Tiso gene 10897 Tiso gene 6299
3.2.1.58-RXN	Probable glucan 1,3-beta-glucosidase A	EC-3.2.1.58	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 16125
3.2.1.6-RXN	Endo- -beta-glucanase	EC-3.2.1.6	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 12892
3.2.1.73-RXN	Endo- -beta-glucanase	EC-3.2.1.73	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 12892
3.2.1.78-RXN	Endo-beta- -mannanase	EC-3.2.1.78	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 8816	PWY-7456
3.2.1.84-RXN	Neutral alpha-glucosidase ab	EC-3.2.1.84	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 2588
3.2.1.91-RXN	Probable 1,4-beta-D-glucan cellobiohydrolase C	EC-3.2.1.91	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 2906	PWY-6788
3.2.2.21-RXN	Dna-3-methyladenine glycosylase i 3-methyladenine dna glycosylase	EC-3.2.2.21	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 7738 Tiso gene 15814
3.2.2.23-RXN	Formamidopyrimidine-dna glycosylase Endonuclease iii 8-oxoguanine dna glycosylase isoform 1b N-glycosylase dna lyase	EC-3.2.2.23	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 9068 Tiso gene 14609 Tiso gene 1280 Tiso gene 6558 Tiso gene 16992
3.3.2.8-RXN	Limonene-12-epoxide hydrolase protein	EC-3.3.2.8	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 15422	PWY-5923
3.3.2.9-RXN	2-hydroxy-6-oxohepta- -dienoate hydrolase	EC-3.3.2.9	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6877
3.4.11.14-RXN	Puromycin-sensitive aminopeptidase	EC-3.4.11.14	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 860
3.4.11.18-RXN	Methionine aminopeptidase	EC-3.4.11.18	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 5715 Tiso gene 3182 Tiso gene 4247
3.4.11.2-RXN	Aminopeptidase n Membrane aminopeptidase i	EC-3.4.11.2	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 16906 Tiso gene 860
3.4.11.21-RXN	Probable aspartyl aminopeptidase	EC-3.4.11.21	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 9879
3.4.11.5-RXN	Proline iminopeptidase	EC-3.4.11.5	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation	Tiso gene 6098 Tiso gene 879 Tiso gene 6057 Tiso gene 6058
3.4.11.9-RXN	Xaa-pro aminopeptidase	EC-3.4.11.9	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation	Tiso gene 13489 Tiso gene 14456 Tiso gene 13488 Tiso gene 16185
3.4.14.9-RXN	Tripeptidyl-peptidase i	EC-3.4.14.9	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 11758
3.4.16.4-RXN	Beta-lactamase	EC-3.4.16.4	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 18870
3.4.16.5-RXN	Carboxypeptidase Y homolog A	EC-3.4.16.5	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 514
3.4.17.11-RXN	Glutamate carboxypeptidase 2	EC-3.4.17.11	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 5253
3.4.21.107-RXN	Protease do	EC-3.4.21.107	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 15772
3.4.21.112-RXN	Membrane-bound transcription factor site-1 protease	EC-3.4.21.112	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6542 Tiso gene 6543
3.4.21.4-RXN	Trypsin family Trypsin	EC-3.4.21.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 2777 Tiso gene 1761 Tiso gene 4842 Tiso gene 13074 Tiso gene 12875 Tiso gene 17883 Tiso gene 13684 Tiso gene 1341 Tiso gene 20549 Tiso gene 8820 Tiso gene 4147 Tiso gene 19324 Tiso gene 1997
3.4.21.50-RXN	Lysyl endopeptidase	EC-3.4.21.50	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 11193
3.4.21.53-RXN	Lon protease homolog, mitochondrial Lon Protease	EC-3.4.21.53	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 4277 Tiso gene 7032
3.4.21.83-RXN	Oligopeptidase b	EC-3.4.21.83	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 1718
3.4.21.92-RXN	ATP-dependent Clp protease proteolytic subunit	EC-3.4.21.92	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 10324 Tiso gene 11705 Tiso gene 10005 Tiso gene 999
3.4.22.34-RXN	Asparaginyl endopeptidase	EC-3.4.22.34	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 17668
3.4.24.11-RXN	Neutral endopeptidase	EC-3.4.24.11	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 15103
3.4.24.59-RXN	Mitochondrial intermediate peptidase	EC-3.4.24.59	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10069
3.4.24.64-RXN	Mitochondrial processing peptidase	EC-3.4.24.64	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation	Tiso gene 5405
3.4.24.71-RXN	Endothelin-converting enzyme 1	EC-3.4.24.71	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 3765
3.4.25.1-RXN	26S protease regulatory subunit 7 26S protease regulatory subunit 8 homolog B	EC-3.4.25.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 19087 Tiso gene 1855 Tiso gene 16496 Tiso gene 11443 Tiso gene 18135 Tiso gene 3310 Tiso gene 11901 Tiso gene 5953 Tiso gene 7332 Tiso gene 20415 Tiso gene 2549
3.5.1.27-RXN	Polypeptide deformylase	EC-3.5.1.88	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 14998
3.5.1.52-RXN	Peptide-n4-(n-acetyl-beta-glucosaminyl)asparagine amidase	EC-3.5.1.52	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation	Tiso gene 18090 Tiso gene 18091
3.5.1.88-RXN	Polypeptide deformylase	EC-3.5.1.88	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 14998
3.5.1.98-RXN	Sir2-family protein hdac1 Histone deacetylase ORF Histone deacetylase 7a Histone deacetylase 1	EC-3.5.1.98	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 10459 Tiso gene 17880 Tiso gene 17340 Tiso gene 12946 Tiso gene 12131 Tiso gene 16490 Tiso gene 3315 Tiso gene 17377 Tiso gene 275 Tiso gene 18096 Tiso gene 727 Tiso gene 19850 Tiso gene 18920
3.5.2.17-RXN	5-hydroxyisourate hydrolase	EC-3.5.2.17	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation	Tiso gene 13181	PWY-7394 PWY-5691
3.5.5.1-RXN	Nitrilase	EC-3.5.5.1	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10996
3.6.1.41-RXN	Metallophosphatase	EC-3.6.1.41	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation	Tiso gene 6311 Tiso gene 19348 Tiso gene 19347
3.6.3.1-RXN	ORF Haloacid dehalogenaselike hydrolase family protein Atpase	EC-3.6.3.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 13202 Tiso gene 7790 Tiso gene 13203 Tiso gene 13177 Tiso gene 11648 Tiso gene 7789
3.6.3.8-RXN	Calcium-transporting ATPase 1, endoplasmic reticulum-type	EC-3.6.3.8	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 10760
3.6.4.1-RXN	Myosin atpase	EC-3.6.4.1	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 8826 Tiso gene 9060
3.6.4.4-RXN	Kinesin	EC-3.6.4.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9800 Tiso gene 16240 Tiso gene 18523 Tiso gene 12881 Tiso gene 15652 Tiso gene 14940 Tiso gene 1492 Tiso gene 5584 Tiso gene 2393 Tiso gene 10834 Tiso gene 10355 Tiso gene 10356 Tiso gene 646 Tiso gene 14941 Tiso gene 6071
3.6.4.6-RXN	Vesicle-fusing ATPase	EC-3.6.4.6	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 1145
3.8.1.11-RXN	Had family hydrolase	EC-3.8.1.11	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 3200
3PGAREARR-RXN	Phosphoglycerate mutase Bisphosphoglycerate-dependent phosphoglycerate mutase ORF Plastid phosphoglycerate mutase protein	EC-5.4.2.12	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 16271 Tiso gene 5468 Tiso gene 14530 Tiso gene 7201 Tiso gene 20311 Tiso gene 2365 Tiso gene 10516 Tiso gene 16754 Tiso gene 9922 Tiso gene 2667 Tiso gene 15391 Tiso gene 2841 Tiso gene 15048 Tiso gene 14212 Tiso gene 9923 Tiso gene 14664	PWY-1042 P341-PWY PWY-2221 GLUCONEO-PWY GLYCOLYSIS PWY-6901 PWY-7218 P124-PWY PWY-6886 PWY-5723 PWY-6142 PWY-5484 PWY-7124 PWY-7003
4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN	Probable gamma hydroxybutyrate dehydrogenase Gamma hydroxybutyrate dehydrogenase	EC-1.1.1.61	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 777 Tiso gene 91	PWY-5022 PWY-5677
4-HYDROXYPHENYLPYRUVATE-DIOXYGENASE-RXN	4-hydroxyphenylpyruvate dioxygenase ORF	EC-1.13.11.27	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 18328 Tiso gene 18976 Tiso gene 18977	PWY-1581 PWY-7432 TYRFUMCAT-PWY PWY-1422
4-NITROPHENYLPHOSPHATASE-RXN	Phosphoglycolate phosphatase 2 ORF	EC-3.1.3.41	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 5996 Tiso gene 442 Tiso gene 6690 Tiso gene 18054 Tiso gene 15176 Tiso gene 6236 Tiso gene 15559 Tiso gene 18651 Tiso gene 6980 Tiso gene 15498
4.1.2.20-RXN	2-dehydro-3-deoxyglucarate aldolase	EC-4.1.2.20	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 16237
4.2.1.58-RXN	Polyketide synthase Β-hydroxybutyryl acyl carrier protein (ACP) dehydrase Β-hydroxybutyryl acyl carrier protein dehydrase Enoyl acyl carrier protein hydrase Crotonyl acyl carrier protein hydratase 3-hydroxybutyryl acyl carrier protein dehydratase	EC-2.3.1.86 EC-2.3.1.85 EC-4.2.1.59	Manual Annotation	Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation	Tiso gene 6884 Tiso gene 13394 Tiso gene 136 Tiso gene 500 Tiso gene 135 Tiso gene 10876	PWY-5971 PWY-5994 PWY-7388
4.2.1.59-RXN	Polyketide synthase	EC-2.3.1.86 EC-2.3.1.85 EC-4.2.1.59	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-synechocystis	Tiso gene 500 Tiso gene 13394 Tiso gene 10876 Tiso gene 135 Tiso gene 6884 Tiso gene 6885 Tiso gene 136	PWY-5971 PWY-5994
4.2.1.61-RXN	Polyketide synthase Β-hydroxypalmitoyl-acyl carrier protein dehydrase Β-hydroxypalmitoyl thioester dehydratase Β-hydroxypalmityl-ACP dehydrase	EC-2.3.1.86 EC-2.3.1.85 EC-4.2.1.59	Manual Annotation	Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation	Tiso gene 136 Tiso gene 13394 Tiso gene 10876 Tiso gene 500 Tiso gene 6884 Tiso gene 135	PWY-5971 PWY-5994
4.2.99.18-RXN	Formamidopyrimidine-dna glycosylase Endonuclease iii Dna-(apurinic or apyrimidinic site) lyase	EC-4.2.99.18	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 1280 Tiso gene 5102 Tiso gene 14609 Tiso gene 6558 Tiso gene 17380
4.4.1.14-RXN	1-aminocyclopropane-1-carboxylate synthase	EC-4.4.1.14	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 8455	ETHYL-PWY PWY-7270
4OHBENZOATE-OCTAPRENYLTRANSFER-RXN	4-hydroxybenzoate octaprenyltransferase	EC-2.5.1.39	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 4719	PWY-6708 PWY-5870
5-NUCLEOTID-RXN	5 -nucleotidase 5 deoxy cytosolic type c protein Probable cytosolic imp-gmp specific 5 -nucleotidase ORF	EC-3.1.3.5	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 6988 Tiso gene 13929 Tiso gene 14435 Tiso gene 5911 Tiso gene 6640 Tiso gene 14434 Tiso gene 14246
5-OXOPROLINASE-ATP-HYDROLYSING-RXN	5-oxoprolinase	EC-3.5.2.9	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 3358 Tiso gene 3359	PWY-4041
5.3.4.1-RXN	Nucleoredoxin ORF Probable protein disulfide-isomerase	EC-5.3.4.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 15704 Tiso gene 475 Tiso gene 4246 Tiso gene 4244 Tiso gene 7350 Tiso gene 14313
5.4.99.17-RXN	ORF	EC-5.4.99.17	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 12198	PWY-7072 PWY-6098
5.99.1.2-RXN	Dna topoisomerase Dna topoisomerase1	EC-5.99.1.2	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 3425 Tiso gene 1740 Tiso gene 5748 Tiso gene 5749 Tiso gene 14333 Tiso gene 200 Tiso gene 10513 Tiso gene 5035 Tiso gene 1739 Tiso gene 5036 Tiso gene 1291 Tiso gene 5747 Tiso gene 6569
5.99.1.3-RXN	Dna topoisomerase ORF Dna topoisomerase 6 subunit a Dna topoisomerase 2	EC-5.99.1.3	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 12629 Tiso gene 6569 Tiso gene 828 Tiso gene 3610 Tiso gene 3396 Tiso gene 829 Tiso gene 3728 Tiso gene 1291 Tiso gene 3374
6-PHOSPHOFRUCTO-2-KINASE-RXN	ORF Fructose- -bisphosphatase Fructose- -bisphophatase	EC-2.7.1.105	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation	Tiso gene 2100 Tiso gene 892 Tiso gene 804 Tiso gene 893 Tiso gene 15398	PWY66-423
6.3.2.25-RXN	Tubulin-tyrosine ligase	EC-6.3.2.25	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 15094 Tiso gene 17234 Tiso gene 5828 Tiso gene 17450 Tiso gene 17589 Tiso gene 20330 Tiso gene 4516 Tiso gene 10591 Tiso gene 9268 Tiso gene 15093 Tiso gene 3379 Tiso gene 14575 Tiso gene 10440
6.3.5.6-RXN	Glutamyl-tRNA(Gln) amidotransferase subunit A	EC-6.3.5.6	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 12219 Tiso gene 9908	PWY490-4
6.3.5.7-RXN	Glutamyl-tRNA(Gln) amidotransferase subunit A	EC-6.3.5.7	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 12219	PWY-5921
6PFRUCTPHOS-RXN	Pyrophosphate-dependent phosphofructose kinase	EC-2.7.1.11	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Manual-primary network Orthology-creinhardtii	Tiso gene 5733 Tiso gene 596	PWY-1042 GLYCOLYSIS PWY-7385 PWY-1861 ANAGLYCOLYSIS-PWY PWY-5484
6PGLUCONOLACT-RXN	ORF 6-phosphogluconolactonase	EC-3.1.1.31	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Manual-primary network Orthology-creinhardtii	Tiso gene 10799 Tiso gene 5901 Tiso gene 15950 Tiso gene 8585 Tiso gene 20412	P122-PWY RUMP-PWY OXIDATIVEPENT-PWY GLYCOLYSIS-E-D
ACETALD-DEHYDROG-RXN	ORF	EC-1.2.1.10	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-creinhardtii	Tiso gene 2052 Tiso gene 7649	PWY4LZ-257 PWY-5436 PWY-7180 PWY-5162 PWY-7085 PWY-6587 PHOSPHONOTASE-PWY P161-PWY P122-PWY ETOH-ACETYLCOA-ANA-PWY PWY-5480 FERMENTATION-PWY
ACETATE--COA-LIGASE-RXN	Acetyl-coenzyme a synthetase	EC-6.2.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 3617 Tiso gene 1612 Tiso gene 3616	PWY66-161 PWY66-21 PWY66-162 PWY0-1313 PWY-6672 PWY-7118
ACETOACETATE-DECARBOXYLASE-RXN		EC-4.1.1.4	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation		PWY66-367 PWY-5451 PWY-6588 PWY-7466 PWY-6876
ACETOLACTREDUCTOISOM-RXN	2,3-Dihydroxy-3-methylbutanoate:DP+ oxidoreductase (isomerizing), chloroplast	EC-1.1.1.86	Orthology Manual Annotation	Pantograph Pathwaytools	Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 10173	VALSYN-PWY PWY-7111
ACETOLACTSYN-RXN	Acetolactate synthase catalytic subunit, mitochondrial	EC-2.2.1.6	Manual Annotation	Pathwaytools	Manual-primary network Annotation-experimental annotation	Tiso gene 11362	VALSYN-PWY PWY-7111 PWY-6389 PWY-5938 PWY-5939
ACETOOHBUTREDUCTOISOM-RXN	2,3-Dihydroxy-3-methylbutanoate:DP+ oxidoreductase (isomerizing), chloroplast	EC-1.1.1.86	Orthology Manual Annotation	Pantograph Pathwaytools	Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 10173	PWY-5103 ILEUSYN-PWY
ACETOOHBUTSYN-RXN	2-aceto-2-hydroxy-butyrate synthase Acetolactate synthase catalytic subunit, mitochondrial	EC-2.2.1.6	Manual Annotation	Pathwaytools	Manual-primary network Annotation-experimental annotation	Tiso gene 11362	PWY-5103 ILEUSYN-PWY PWY-5101 PWY-5104
ACETYL-COA-CARBOXYLTRANSFER-RXN		EC-6.4.1.2	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Annotation-experimental annotation Manual-primary network Orthology-esiliculosus	Tiso gene 3800 Tiso gene 5029 Tiso gene 2812 Tiso gene 7965	PWY-7388 PWY-6722 PWY-5743 PWY-5744 PWY-5789 PWY-6679 PWY-4381
ACETYLCHOLINESTERASE-RXN	Para-nitrobenzyl esterase	EC-3.1.1.7	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 4650
ACETYLGLUTKIN-RXN	Acetylglutamate kinase	EC-2.7.2.8	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 13144	PWY-5154 GLUTORN-PWY ARGSYNBSUB-PWY
ACETYLORNTRANSAM-RXN	Acetylornithine aminotransferase	EC-2.6.1.11	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-creinhardtii Orthology-synechocystis Orthology-esiliculosus	Tiso gene 11231	PWY-5154 GLUTORN-PWY ARGSYNBSUB-PWY
ACID-PHOSPHATASE-RXN	Acid phosphatase Purple acid phosphatase-like protein ORF Histidine acid phosphatase domain containing 2a	EC-3.1.3.2	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 17610 Tiso gene 4497 Tiso gene 11838 Tiso gene 15256 Tiso gene 5996 Tiso gene 17310 Tiso gene 8159 Tiso gene 17625 Tiso gene 17309	PWY-6348
ACONITATEDEHYDR-RXN			Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-synechocystis	Tiso gene 13007	FERMENTATION-PWY PWY-5913 PWY66-398 PWY-5690 REDCITCYC PWY-5392 P23-PWY P105-PWY GLYOXYLATE-BYPASS PWY-6969 PWY-6728 PWY-6549 PWY-7254 PWY-7124 PWY-5750 TCA
ACONITATEHYDR-RXN	Cis-aconitate hydratase		Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 13007	PWY-5913 PWY-6969 PWY-6549 PWY-5392 P23-PWY PWY-7124 P105-PWY GLYOXYLATE-BYPASS FERMENTATION-PWY PWY-6728 REDCITCYC PWY-7254 PWY-5690 PWY66-398 TCA
ACP-S-ACETYLTRANSFER-RXN	Polyketide synthase	EC-2.3.1.86 EC-2.3.1.85 EC-2.3.1.38	Orthology Manual Annotation	Pantograph Pathwaytools	Manual-primary network Orthology-athaliana Annotation-in-silico annotation Orthology-synechocystis	Tiso gene 13394 Tiso gene 15991 Tiso gene 10876 Tiso gene 136 Tiso gene 500 Tiso gene 135	PWY-5966 FASYN-INITIAL-PWY
ACSERLY-RXN	Cysteine synthase Cog0031: cysteine synthase Cysteine	EC-2.5.1.47	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 6110 Tiso gene 12184 Tiso gene 2283 Tiso gene 819 Tiso gene 17043 Tiso gene 7852	CYSTSYN-PWY
ACYL-COA-HYDROLASE-RXN	Acyl-coenzyme a thioesterase mitochondrial-like ORF Thioesterase superfamily member 2	EC-3.1.2.20	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 801 Tiso gene 10984 Tiso gene 7477 Tiso gene 800
ACYL-COA-OXIDASE-RXN	Acyl-coenzyme a oxidase	EC-1.3.3.6	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 18566	PWY-7007
ACYLAMINOACYL-PEPTIDASE-RXN	Acylamino-acid-releasing enzyme	EC-3.4.19.1	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 3550
ACYLCARNITINE-HYDROLASE-RXN	Para-nitrobenzyl esterase	EC-3.1.1.28	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 4650
ACYLCOADEHYDROG-RXN	Acyl- dehydrogenase Acyl-CoA dehydrogenase Fatty acyl coenzyme A dehydrogenase Acyl coenzyme A dehydrogenase Fatty-acyl-CoA dehydrogenase General acyl CoA dehydrogenase Medium-chain acyl-coenzyme A dehydrogenase Long-chain acyl coenzyme A dehydrogenase Long-chain acyl-CoA dehydrogenase	EC-1.3.8	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 10643 Tiso gene 6475 Tiso gene 16113 Tiso gene 7447 Tiso gene 14511 Tiso gene 8272 Tiso gene 5449 Tiso gene 16631 Tiso gene 8271 Tiso gene 883 Tiso gene 6295	FAO-PWY
ACYLCOASYN-RXN	2,3,4-saturated fatty acyl-CoA synthetase Polyketide synthase Long chain acyl- synthetase Acyl- synthetase ORF Acyl-activating enzyme Fatty acid thiokinase (long-chain)	EC-6.2.1.3	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 7855 Tiso gene 13394 Tiso gene 348 Tiso gene 500 Tiso gene 10876 Tiso gene 9394 Tiso gene 136 Tiso gene 135 Tiso gene 4191	PWY-5136 PWY-7288 FAO-PWY PWY66-391
ACYLPHOSPHATASE-RXN	Acylphosphatase	EC-3.6.1.7	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 13909
ADDALT-RXN	Aldo-keto reductase family 4 member c9 isoform x2 ORF	EC-3.5.4.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 19373 Tiso gene 18322	PWY-7179-1 PWY-7179
ADENODEAMIN-RXN	ORF Aldo-keto reductase family 4 member c9 isoform x2	EC-3.5.4.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 18322 Tiso gene 19373	PWY0-1296 PWY-6609 PWY-6611 SALVADEHYPOX-PWY
ADENOSINE-KINASE-RXN	ORF	EC-2.7.1.20	Manual Annotation	Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation	Tiso gene 12078	PWY-6619
ADENOSINE-NUCLEOSIDASE-RXN	Inosine-uridine preferring nucleoside hydrolase	EC-3.2.2.7	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 9396	PWY-6605
ADENOSYLHOMOCYSTEINASE-RXN	Adenosylhomocysteinase 1	EC-3.3.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 14191	METHIONINE-DEG1-PWY PWY-5041
ADENYL-KIN-RXN	Adenylate kinase (Fragment) n ORF Adenylate kinase Adenylate kinase 4 Central pair complex 1	EC-2.7.4.3	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 694 Tiso gene 5837 Tiso gene 12257 Tiso gene 4816 Tiso gene 5839 Tiso gene 19036 Tiso gene 12256 Tiso gene 8576 Tiso gene 5387 Tiso gene 5081 Tiso gene 1453 Tiso gene 14116 Tiso gene 13477 Tiso gene 5388 Tiso gene 805 Tiso gene 3353 Tiso gene 19734	PWY-7219
ADENYLATECYC-RXN	Adenylate cyclase	EC-4.6.1.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 13108 Tiso gene 8950 Tiso gene 9251 Tiso gene 1107 Tiso gene 16074 Tiso gene 34 Tiso gene 16294 Tiso gene 16143 Tiso gene 17342 Tiso gene 10744 Tiso gene 16542 Tiso gene 14301 Tiso gene 6404 Tiso gene 15744 Tiso gene 6871 Tiso gene 5483 Tiso gene 10495 Tiso gene 9865
ADENYLOSUCCINATE-SYNTHASE-RXN	Adenylosuccinate synthase Adenylosuccinate synthetase	EC-6.3.4.4	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 6453 Tiso gene 743	PWY-7219
ADENYLYLSULFATASE-RXN	Transcription factor bhlh140-like	EC-3.6.2.1	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6339 Tiso gene 6338
ADPREDUCT-RXN	ADP reductase Ribonucleoside-diphosphate reductase	EC-1.17.4.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 10617 Tiso gene 9916 Tiso gene 10138 Tiso gene 9915	PWY-7220 PWY-7227
ADPSUGPPHOSPHAT-RXN	ADP-sugar pyrophosphatase	EC-3.6.1.21	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 7189
AICARSYN-RXN		EC-4.3.2.2	Manual Annotation	Pathwaytools	Manual-primary network Annotation-in-silico annotation		PWY-6123 PWY-6124 PWY-7234
AICARTRANSFORM-RXN	Bifunctional purine biosynthesis 5-aminoimidazole-4-carboxamide ribonucleotide transformylase	EC-2.1.2.3	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 18420	PWY-6123 PWY-6124
AIRCARBOXY-RXN	Phosphoribosylaminoimidazole carboxylase	EC-4.1.1.21	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 16011	PWY-6124
AIRS-RXN		EC-6.3.3.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-synechocystis	Tiso gene 1369	PWY-6121 PWY-6122 PWY-6277
AKBLIG-RXN	Glycine c-acetyltransferase	EC-2.3.1.29	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 3555	THREONINE-DEG2-PWY
ALANINE--GLYOXYLATE-AMINOTRANSFERASE-RXN	Acetylornithine aminotransferase	EC-2.6.1.44	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-athaliana Orthology-esiliculosus	Tiso gene 11231 Tiso gene 6134 Tiso gene 5726	GLYSYN-ALA-PWY
ALANINE--TRNA-LIGASE-RXN	Threonine alanine trna ligase subfamily protein ORF Alanyl-trna synthetase	EC-6.1.1.7	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 2298 Tiso gene 3249 Tiso gene 18609 Tiso gene 19573 Tiso gene 18607	TRNA-CHARGING-PWY
ALANINE-AMINOTRANSFERASE-RXN	Alanine aminotransferase mitochondrial Alanine aminotransferase	EC-2.6.1.2	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 5959 Tiso gene 10957	ALANINE-DEG3-PWY PWY-7383 PWY-7117 ALACAT2-PWY PWY-7115 ALANINE-SYN2-PWY
ALARACECAT-RXN	ORF	EC-5.1.1.1	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 20278	PWY-7383 ALANINE-VALINESYN-PWY ALADEG-PWY
ALCOHOL-DEHYDROG-GENERIC-RXN	Polyketide synthase ORF	EC-1.1.1.1	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 5424 Tiso gene 6563 Tiso gene 7649 Tiso gene 6562 Tiso gene 5425
ALCOHOL-DEHYDROG-RXN	Polyketide synthase ORF	EC-1.1.1.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-synechocystis	Tiso gene 5424 Tiso gene 6563 Tiso gene 5425 Tiso gene 7649 Tiso gene 18459 Tiso gene 6562	PWY66-21 PWY4LZ-257 PWY-7118 PWY-6587 PWY-6333 PWY-5486 P161-PWY ETOH-ACETYLCOA-ANA-PWY P122-PWY PWY-5480 FERMENTATION-PWY
ALCOHOL-O-ACETYLTRANSFERASE-RXN	ORF	EC-2.3.1.84	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10528
ALDEHYDE-DEHYDROGENASE-NADORNOP+-RXN	Aldehyde dehydrogenase	EC-1.2.1.5	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 7322
ALDEHYDE-REDUCTASE-RXN	Oxidoreductase Aldose reductase Aldo keto reductase	EC-1.1.1.21	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 8988 Tiso gene 7799 Tiso gene 18748 Tiso gene 7800
ALDOSE-1-EPIMERASE-RXN	Aldose 1-epimerase	EC-5.1.3.3	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation	Tiso gene 19779 Tiso gene 17734	PWY0-1466
ALDOSE1EPIM-RXN	Aldose 1-epimerase	EC-5.1.3.3	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation	Tiso gene 19779 Tiso gene 17734	PWY-6317 PWY66-422
ALKAPHOSPHA-RXN	Alkaline phosphatase d Alkaline phosphatase ORF	EC-3.1.3.1	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 9372 Tiso gene 10738 Tiso gene 3271
ALLANTOICASE-RXN	Allantoicase	EC-3.5.3.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 15504	PWY-5697
ALLANTOINASE-RXN		EC-3.5.2.5	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation		PWY-5697 PWY-5698
ALLYSINE-DEHYDROG-RXN	Polyketide synthase ORF	EC-1.2.1.31	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 5424 Tiso gene 6563 Tiso gene 5425 Tiso gene 6562 Tiso gene 16719
ALPHAGALACTOSID-RXN	Alpha-galactosidase	EC-3.2.1.22	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 2588 Tiso gene 16101 Tiso gene 8673 Tiso gene 4615 Tiso gene 3392	PWY0-1301
AMIDASE-RXN	Amidase	EC-3.5.1.4	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 13682
AMINOACYLASE-RXN	Acy1-like metalloprotease	EC-3.5.1.14	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 16879
AMINOBUTDEHYDROG-RXN	Aminobutyraldehyde dehydrogenase	EC-1.2.1.19	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 17322	PUTDEG-PWY PWY-2 PWY-3
AMINOCYL-TRNA-HYDROLASE-RXN	Peptidyl-trna hydrolase	EC-3.1.1.29	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 7443 Tiso gene 13800 Tiso gene 14300
AMP-DEAMINASE-RXN	Amp deaminase	EC-3.5.4.17 EC-3.5.4.6	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1778	PWY-6596
AMP-DEPHOSPHORYLATION-RXN	5 -nucleotidase 5 deoxy cytosolic type c protein Probable cytosolic imp-gmp specific 5 -nucleotidase ORF	EC-3.1.3.5	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 6640 Tiso gene 14435 Tiso gene 6988 Tiso gene 14434 Tiso gene 13929 Tiso gene 5911 Tiso gene 14246	SALVADEHYPOX-PWY
AMPSYN-RXN		EC-4.3.2.2	Manual Annotation	Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation		PWY-7219
ANTHRANSYN-RXN	Anthranilate synthase	EC-4.1.3.27	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 11176	TRPSYN-PWY PWY-5958 PWY-6661 PWY-6660
APIGNAR-RXN	Naringenin chalcone isomerase Atp-dependent rna helicase dhx30-like	EC-5.5.1.6	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 13414 Tiso gene 9838	PWY-7397 PWY1F-FLAVSYN PWY-6787
APYRASE-RXN	ORF	EC-3.6.1.5	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 12899 Tiso gene 20236
ARGINASE-RXN		EC-3.5.3.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 4415	ARGASEDEG-PWY PWY-6922 ARG-PRO-PWY ARG-GLU-PWY PWY-4984 PWY-6305 CITRULBIO-PWY
ARGININE--TRNA-LIGASE-RXN	Arginyl-trna synthetase Arginine-trna ligase	EC-6.1.1.19	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 12997 Tiso gene 16360	TRNA-CHARGING-PWY
ARGININE-2-MONOOXYGENASE-RXN		EC-1.13.12.1	Annotation	Pathwaytools	Annotation-in-silico annotation		ARGDEG-V-PWY
ARGSUCCINLYA-RXN	Argininosuccinate lyase	EC-4.3.2.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 2485	PWY-4984 ARGSYN-PWY PWY-5154 ARGSYNBSUB-PWY PWY-4983 PWY-7400
ARGSUCCINSYN-RXN	Argininosuccinate synthase	EC-6.3.4.5	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 12592	PWY-5154 ARGSYN-PWY PWY-4984 ARGSYNBSUB-PWY PWY-4983 PWY-7400
ARYL-ALCOHOL-DEHYDROGENASE-NADP+-RXN	Probable voltage-gated potassium channel subunit beta	EC-1.1.1.91	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 8612
ARYLAMINE-N-ACETYLTRANSFERASE-RXN	Arylamine n-acetyltransferase	EC-2.3.1.5	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation	Tiso gene 9942
ARYLSULFAT-RXN	Sulfatase	EC-3.1.6.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 15834 Tiso gene 5811 Tiso gene 9519 Tiso gene 11338 Tiso gene 7286 Tiso gene 15619 Tiso gene 15833
ASNSYNA-RXN	Asparagine synthetase Asparagine synthetase domaincontaining protein putat Aspartate-ammonia ligase	EC-6.3.1.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 7495 Tiso gene 1462 Tiso gene 2973	ASPARAGINESYN-PWY
ASNSYNB-RXN	Asparagine synthetase Asparagine synthetase domaincontaining protein putat	EC-6.3.5.4	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 2973 Tiso gene 7495	ASPARAGINE-BIOSYNTHESIS
ASPAMINOTRANS-RXN	Aminotransferase Aspartate aminotransferase	EC-2.6.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 17809 Tiso gene 6815 Tiso gene 17718 Tiso gene 13538 Tiso gene 12889 Tiso gene 15680	PWY-5913 MALATE-ASPARTATE-SHUTTLE-PWY PWY-7383 ASPARTATE-DEG1-PWY ASPARTATESYN-PWY PWY-7117 GLUTDEG-PWY PWY-7115 ASPARAGINE-DEG1-PWY-1
ASPARAGHYD-RXN	Asparaginase	EC-3.5.1.38 EC-3.5.1.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-creinhardtii Orthology-synechocystis Orthology-esiliculosus	Tiso gene 3570 Tiso gene 19398 Tiso gene 17477	ASPASN-PWY ASPARAGINE-DEG1-PWY ASPARAGINE-DEG1-PWY-1
ASPARAGINE--TRNA-LIGASE-RXN	Mitochondrial carrier (bou s-adenosylmethionine carrier) ORF Mitochondrial substrate carrier family protein	EC-6.1.1.22	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation	Tiso gene 6065 Tiso gene 9304 Tiso gene 13908 Tiso gene 9303 Tiso gene 9908	TRNA-CHARGING-PWY
ASPARTATE--TRNA-LIGASE-RXN	Aspartyl-trna synthetase	EC-6.1.1.12	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 7126 Tiso gene 17185 Tiso gene 13081	TRNA-CHARGING-PWY
ASPARTATE-RACEMASE-RXN	ORF	EC-5.1.1.13	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 16719
ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN	Aspartate-semialdehyde dehydrogenase	EC-1.2.1.11	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 18603	HOMOSERSYN-PWY PWY-7153 DAPLYSINESYN-PWY PWY-2942 PWY-2941 PWY-6559 PWY-6562 PWY-5097 P101-PWY
ASPARTATEKIN-RXN	Bifunctional aspartokinase homoserine dehydrogenase Aspartokinase Homoserine dehydrogenase	EC-2.7.2.4	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 16097 Tiso gene 4345 Tiso gene 13809 Tiso gene 17057	HOMOSERSYN-PWY PWY-7153 DAPLYSINESYN-PWY PWY-2942 PWY-2941 PWY-6559 PWY-6562 PWY-5097 P101-PWY
ASPARTOACYLASE-RXN	Aspartoacylase Probable aspartoacylase	EC-3.5.1.15	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 16773 Tiso gene 9219
ASPCARBTRANS-RXN	Protein pyr1-3	EC-2.1.3.2	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 13527	PWY-7790 PWY-7791 PWY-5686
ATPASE-RXN	Helicase mov-10- -like Pleiotropic drug resistance proteins (pdr1-15) abc superfamily Hsp104 ORF Abc transporter Dynein-1-alpha heavy flagellar inner arm i1 complex Atp-binding cassette superfamily Atp-dependent metalloprotease Uncharacterized conserved protein Atp-binding cassette sub-family f member 3 Replication factor c subunit 2 Atp-binding cassettetransporter Atp-binding cassette sub-family a member 3-like Member of the hsp104 clp superfamily Atp-binding cassette transporter Dynein-1-beta heavy flagellar inner arm i1 complex Von willebrand factor a domain-containing protein 8-like Atp-binding cassette sub-family g member 2 At1g33290 Atpase family aaa domain-containing protein 2b- partial Replication factor c subunit 3 Long-chain fatty acyl- synthetase Replication control protein 1 like Aaa family cdc48 subfamily Adenylate guanylate Dynein heavy chain axonemal Replication factor c subunit 1 Dynein heavy chain 2 E3 ubiquitin-protein ligase rnf213-like Daunorubicin resistance abc transporter atp-binding subunit family protein Nfx1-type zinc finger-containing protein 1 Dna-binding protein smubp-2 Abc transporter-like protein Cytosolic fe-s cluster assembly factor nubp1 homolog Uncharacterized transmembrane protein ddb g0290641 Dynein heavychain Inner arm group 5 Dynein alphaflagellarouterarm Isoform m of dna helicase mcm9 26s proteaseregulatorysubunit6bhomolog Atpase Abc transporter f family member 3 Ensangp00000010790 Atp-dependent zinc metalloprotease Trna-splicing endonuclease positive effector Ciliary dyneinheavy Adenylate kinase domain-containing protein 1 Gtpase der Atp-binding cassette subfamily member group aoh protein 7 Uridine kinase Dynein heavychainaxonemal Atp-binding cassette Sporangia induceddyneinheavychain Origin recognition complex subunit 4 Atpase aaa Endonuclease 2 Fidgetin-like protein1 Replication factor c subunit 5 Dynein heavy Outer arm dynein beta heavy chain Atpase afg2 protein Atpase family associated with various cellular activities Abc transporter g family protein Sh2 domain containing protein Dynein heavychain2 Atp-binding sub-family g Katanin p60 atpase-containing subunit a-like 2 Dynein heavy chain axonemal-like Type a von willebrand factor domain-containing protein Atp-dependent proteaseatpasesubunit Cytoplasmic dynein 2 heavy chain 1	EC-3.6.4.6 EC-3.6.1.3 EC-3.6.1.15	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Orthology-creinhardtii Annotation-experimental annotation	Tiso gene 79 Tiso gene 11754 Tiso gene 2450 Tiso gene 3754 Tiso gene 19350 Tiso gene 9234 Tiso gene 5825 Tiso gene 1181 Tiso gene 13738 Tiso gene 1984 Tiso gene 3580 Tiso gene 12088 Tiso gene 8601 Tiso gene 623 Tiso gene 570 Tiso gene 13211 Tiso gene 20353 Tiso gene 20581 Tiso gene 4157 Tiso gene 9423 Tiso gene 6599 Tiso gene 2924 Tiso gene 2798 Tiso gene 15351 Tiso gene 5527 Tiso gene 12148 Tiso gene 13325 Tiso gene 2452 Tiso gene 19098 Tiso gene 4693 Tiso gene 14646 Tiso gene 237 Tiso gene 17449 Tiso gene 11923 Tiso gene 16478 Tiso gene 567 Tiso gene 9541 Tiso gene 4692 Tiso gene 9659 Tiso gene 14227 Tiso gene 5005 Tiso gene 621 Tiso gene 13737 Tiso gene 18780 Tiso gene 1358 Tiso gene 1983 Tiso gene 4330 Tiso gene 4026 Tiso gene 13520 Tiso gene 7215 Tiso gene 10771 Tiso gene 12899 Tiso gene 13518 Tiso gene 1790 Tiso gene 4092 Tiso gene 2448 Tiso gene 5013 Tiso gene 1291 Tiso gene 195 Tiso gene 546 Tiso gene 4726 Tiso gene 17616 Tiso gene 1960 Tiso gene 250 Tiso gene 1360 Tiso gene 15465 Tiso gene 16915 Tiso gene 5014 Tiso gene 11155 Tiso gene 13268 Tiso gene 13409 Tiso gene 1672 Tiso gene 18443 Tiso gene 17751 Tiso gene 6592 Tiso gene 5004 Tiso gene 18105 Tiso gene 4192 Tiso gene 2897 Tiso gene 38 Tiso gene 8584 Tiso gene 11012 Tiso gene 1959 Tiso gene 14226 Tiso gene 9262 Tiso gene 8741 Tiso gene 1145 Tiso gene 6012 Tiso gene 8461 Tiso gene 7210 Tiso gene 5826 Tiso gene 1610 Tiso gene 15043 Tiso gene 873 Tiso gene 2451 Tiso gene 17675 Tiso gene 3581 Tiso gene 17201 Tiso gene 8295 Tiso gene 13681 Tiso gene 9959 Tiso gene 13521 Tiso gene 12618 Tiso gene 8950 Tiso gene 7979 Tiso gene 5166 Tiso gene 13264 Tiso gene 6820 Tiso gene 8164 Tiso gene 2206 Tiso gene 601 Tiso gene 18007 Tiso gene 10282 Tiso gene 9263 Tiso gene 10760 Tiso gene 11325 Tiso gene 2889 Tiso gene 9243 Tiso gene 8742 Tiso gene 253 Tiso gene 6838 Tiso gene 6181 Tiso gene 829 Tiso gene 15850 Tiso gene 1917 Tiso gene 14474 Tiso gene 4155 Tiso gene 10823 Tiso gene 6537 Tiso gene 4437 Tiso gene 199 Tiso gene 572 Tiso gene 1306 Tiso gene 1366 Tiso gene 10824 Tiso gene 9114 Tiso gene 7873 Tiso gene 674 Tiso gene 8860 Tiso gene 4595 Tiso gene 8949 Tiso gene 11098 Tiso gene 2447 Tiso gene 569 Tiso gene 11648 Tiso gene 6180 Tiso gene 5525 Tiso gene 10584 Tiso gene 1914 Tiso gene 12953 Tiso gene 2929 Tiso gene 8153 Tiso gene 10981 Tiso gene 5528 Tiso gene 9264 Tiso gene 6822 Tiso gene 4156 Tiso gene 7745 Tiso gene 14113 Tiso gene 9460 Tiso gene 2068 Tiso gene 13653 Tiso gene 5526 Tiso gene 1444 Tiso gene 1611 Tiso gene 1541 Tiso gene 2449 Tiso gene 12185 Tiso gene 5307 Tiso gene 6839 Tiso gene 14239 Tiso gene 14547 Tiso gene 3406 Tiso gene 11192 Tiso gene 20327 Tiso gene 538 Tiso gene 7387 Tiso gene 2631 Tiso gene 7123 Tiso gene 15988 Tiso gene 12149 Tiso gene 9926 Tiso gene 8859 Tiso gene 8763 Tiso gene 4091 Tiso gene 4436 Tiso gene 568 Tiso gene 11689 Tiso gene 5529 Tiso gene 4596 Tiso gene 10221 Tiso gene 14816 Tiso gene 1916 Tiso gene 13522 Tiso gene 9004 Tiso gene 6614
ATPSYN-RXN	V-type proton atpase ORF Vacuolar h+- sector c V-type proton atpase catalytic subunit a Vacuolar h+-atpase v0 subunits a Atp synthase gamma chloroplastic Atp synthase gamma subunit Atp synthase subunit mitochondrial Ycf35 Atp synthase delta mitochondrial V-type proton atpase subunit h V-type protonatpasesubunitd1	EC-3.6.3.14	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 11754 Tiso gene 9460 Tiso gene 12618 Tiso gene 18105 Tiso gene 11192 Tiso gene 5307 Tiso gene 15850 Tiso gene 1366 Tiso gene 7213 Tiso gene 10981 Tiso gene 2798 Tiso gene 1365 Tiso gene 17383 Tiso gene 7215 Tiso gene 11753 Tiso gene 11155 Tiso gene 6012 Tiso gene 6592	PWY-7219
BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN		EC-1.2.1.28	Annotation	Pathwaytools	Annotation-in-silico annotation		PWY-6763 PWY-1501 PWY-6766 TOLUENE-DEG-CATECHOL-PWY PWY-6446 PWY-6444
BENZALDEHYDE-DEHYDROGENASE-NADP+-RXN		EC-1.2.1.7	Annotation	Pathwaytools	Annotation-in-silico annotation		PWY-1501
BETA-GLUCURONID-RXN	Beta-glucuronidase	EC-3.2.1.31	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 13087	PWY-7247
BETA-LACTAMASE-RXN	Beta-lactamase	EC-3.5.2.6	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6745 Tiso gene 18870 Tiso gene 19424 Tiso gene 2989
BETAGALACTOSID-RXN	Β-galactosidase Glycoside hydrolase Polyprotein	EC-3.2.1.108 EC-3.2.1.23	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1398 Tiso gene 12839 Tiso gene 17558	BGALACT-PWY
BILIVERDIN-REDUCTASE-RXN		EC-1.3.1.24	Annotation	Pathwaytools	Annotation-in-silico annotation		PWY-5874
BIOTIN-CARBOXYL-RXN	Acetyl- carboxylase	EC-6.3.4.14	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 7965	PWY0-1264
BIOTINLIG-RXN	ORF	EC-6.3.4.15	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 14184 Tiso gene 8713 Tiso gene 17216	PWY0-1264
BRANCHED-CHAINAMINOTRANSFERILEU-RXN	Branched-chain amino acid aminotransferase	EC-2.6.1.42	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 14984 Tiso gene 17748 Tiso gene 18403	ILEUSYN-PWY ILEUDEG-PWY PWY-5108 PWY-5103 PWY-5101 PWY-5078 PWY-5104
BRANCHED-CHAINAMINOTRANSFERLEU-RXN	Branched-chain amino acid aminotransferase	EC-2.6.1.6 EC-2.6.1.42	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 18403 Tiso gene 14984	PWY-7767 LEU-DEG2-PWY LEUSYN-PWY PWY-5076
BRANCHED-CHAINAMINOTRANSFERVAL-RXN	Branched-chain amino acid aminotransferase	EC-2.6.1.42	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 18403 Tiso gene 14984	VALSYN-PWY VALDEG-PWY ALANINE-VALINESYN-PWY PWY-5057
CARBAMATE-KINASE-RXN		EC-2.7.2.2	Annotation	Pathwaytools	Annotation-experimental annotation		PWY0-41 CITRULLINE-DEG-PWY
CARBODEHYDRAT-RXN	Carbonic anhydrase ORF Beta-type carbonic anhydrase Gamma carbonic anhydrase Alpha ca	EC-4.2.1.1	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 3056 Tiso gene 19413 Tiso gene 18927 Tiso gene 6150 Tiso gene 20230 Tiso gene 7660 Tiso gene 1600 Tiso gene 19414 Tiso gene 9852 Tiso gene 17511
CARBONYL-REDUCTASE-NADPH-RXN	Carbonyl reductase	EC-1.1.1.184	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 20417
CARBOXYLESTERASE-RXN	Alpha beta hydrolase fold protein ORF Serine esterase Sialate o-acetylesterase-like protein Lysophospholipase Alpha beta hydrolase Protein chloroplastic Para-nitrobenzyl esterase	EC-3.1.1.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 1538 Tiso gene 1922 Tiso gene 4606 Tiso gene 17029 Tiso gene 1537 Tiso gene 2556 Tiso gene 9429 Tiso gene 11351 Tiso gene 10066 Tiso gene 4650 Tiso gene 16518 Tiso gene 19778 Tiso gene 12686
CARBOXYMETHYLENEBUTENOLIDASE-RXN	Carboxymethylenebutenolidase	EC-3.1.1.45	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 12835	PWY-6087 PWY-6193
CARBPSYN-RXN	Carbamoyl phosphate synthetase	EC-6.3.5.5	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 4976 Tiso gene 4975 Tiso gene 4685	ARGSYN-PWY PWY-5154 PWY-7790 ARGSYNBSUB-PWY PWY-7400 PWY-7791 PWY-5686
CATAL-RXN		EC-1.11.1.6 EC-1.11.1.21	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-synechocystis	Tiso gene 3006 Tiso gene 11916 Tiso gene 5435 Tiso gene 19683 Tiso gene 11607 Tiso gene 12499 Tiso gene 4990 Tiso gene 15923	PWY-5506 DETOX1-PWY DETOX1-PWY-1
CDPDIGLYSYN-RXN	Phosphatidate cytidylyltransferase	EC-2.7.7.41	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 3522 Tiso gene 2311 Tiso gene 3523	PWY-7817 PWY-5667 PWY0-1319 PWY-5981
CDPKIN-RXN	ORF Adenylate kinase domain-containing protein 1 Nucleoside diphosphate kinase	EC-2.7.4.6	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 16529 Tiso gene 17271 Tiso gene 17272 Tiso gene 195 Tiso gene 9290 Tiso gene 18224	PWY-7205
CDPREDUCT-RXN	Ribonucleoside-diphosphate reductase	EC-1.17.4.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 10617 Tiso gene 9916 Tiso gene 10138 Tiso gene 9915	PWY-7210 PWY-7198 PWY-6545 PWY0-166 PWY-7184
CELLULOSE-SYNTHASE-UDP-FORMING-RXN	Glycosyltransferase family 2 protein	EC-2.4.1.12	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 6390 Tiso gene 322	PWY-1001
CEREBROSIDE-SULFATASE-RXN	Arylsulfatase a	EC-3.1.6.8	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 16078
CHALCONE-ISOMERASE-RXN	Atp-dependent rna helicase dhx30-like	EC-5.5.1.6	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 13414
CHD-RXN	Glucose-methanol-choline oxidoreductase	EC-1.1.99.1	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 16765	CHOLINE-BETAINE-ANA-PWY BETSYN-PWY
CHLORIDE-PEROXIDASE-RXN	Alpha beta-hydrolase	EC-1.11.1.10	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 19107
CHOLESTENONE-5-ALPHA-REDUCTASE-RXN	3-oxo-5-alpha-steroid 4-dehydrogenase 3-oxosteroid Δ4-dehydrogenase Δ4-3-ketosteroid 5α-oxidoreductase	EC-1.3.1.22	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 14327
CHOLINE-KINASE-RXN	Choline ethanolamine kinase	EC-2.7.1.32	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 16805	PWY-7782 PWY-7818 PWY3O-450
CHORISMATE-SYNTHASE-RXN	Chorismate synthase	EC-4.2.3.5	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 9630	PWY-6163
CHORISMATEMUT-RXN	Bifunctional chorismate mutase prephenate dehydratase	EC-5.4.99.5	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 5940	PHESYN PWY-6120 PWY-3462 PWY-3461 PWY-7626 TYRSYN PWY-6627
CITSYN-RXN	Citrate synthase Condensing enzyme Citrate synthesis	EC-2.3.3.16 EC-2.3.3.1	Manual Annotation	Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation	Tiso gene 9602 Tiso gene 9601 Tiso gene 18030 Tiso gene 9603	PWY-5913 PWY-7124 PWY-6969 PWY66-398 REDCITCYC P105-PWY GLYOXYLATE-BYPASS FERMENTATION-PWY PWY-6728 PWY-6549 PWY-7254 PWY-5690 PWY-5750 TCA
COBALADENOSYLTRANS-RXN	Cob alaminadenosyltransferase	EC-2.5.1.17	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 6190	PWY-6268
COENZYME-F420-HYDROGENASE-RXN	Coenzyme f420 hydrogenase	EC-1.12.98.1	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 1396
CORTISONE-ALPHA-REDUCTASE-RXN	Cortisone α-reductase 3-oxo-5-alpha-steroid 4-dehydrogenase Cortisone Δ4-5α-reductase Microsomal steroid reductase (5α) Δ4-3-ketosteroid reductase (5α) Δ4-3-oxosteroid-5α-reductase NADPH:Δ4-3-oxosteroid-5α-oxidoreductase Δ4-5α-reductase	EC-1.3.1.22	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 14327

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