2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN

Reaction 2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 4-methyl-2-oxopentanoate dehydrogenase (acylating)
• ec number:
  • EC-1.2.1
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 2K-4CH3-PENTANOATE[c] + 1 CO-A[c] => 1 CARBON-DIOXIDE[c] + 1 ISOVALERYL-COA[c] + 1 NADH[c]
• With common name(s):
  • 1 NAD+[c] + 1 4-methyl-2-oxopentanoate[c] + 1 coenzyme A[c] => 1 CO2[c] + 1 isovaleryl-CoA[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: CHC_T00010287001_1
  • Source: orthology-galdieria.sulphuraria

Pathways

• LEU-DEG2-PWY, L-leucine degradation I: LEU-DEG2-PWY
  • 3 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-galdieria.sulphuraria
    • Tool: pantograph

External links

• RHEA:
  • 25177
• LIGAND-RXN:
  • R01651