2OXOGLUTARATEDEH-RXN

Reaction 2OXOGLUTARATEDEH-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 2-oxoglutarate dehydrogenase complex
  • 2-oxoglutarate dehydrogenase, E1 component
  • dihydrolipoamide dehydrogenase
• Synonym(s):
  • 2-oxoglutarate dehydrogenation
  • α-ketoglutarate oxidative decarboxylation

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 2-KETOGLUTARATE[c] + 1 CO-A[c] => 1 NADH[c] + 1 SUC-COA[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 NAD+[c] + 1 2-oxoglutarate[c] + 1 coenzyme A[c] => 1 NADH[c] + 1 succinyl-CoA[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: CHC_T00008441001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: CHC_T00008312001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: CHC_T00008441001_1
  • Source: orthology-galdieria.sulphuraria
  • Source: orthology-ectocarpus_siliculosus
• Gene: CHC_T00010287001_1
  • Source: orthology-galdieria.sulphuraria
  • Source: orthology-ectocarpus_siliculosus
• Gene: CHC_T00008312001_1
  • Source: orthology-galdieria.sulphuraria

Pathways

• TCA, TCA cycle I (prokaryotic): TCA
  • 9 reactions found over 10 reactions in the full pathway
• PWY-5690, TCA cycle II (plants and fungi): PWY-5690
  • 9 reactions found over 9 reactions in the full pathway
• PWY-7254, TCA cycle VII (acetate-producers): PWY-7254
  • 7 reactions found over 9 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-galdieria.sulphuraria
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-original_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 27786
• LIGAND-RXN:
  • R08549