RXN-12583

Reaction RXN-12583

• direction:
  • LEFT-TO-RIGHT
• common name:
  • pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)
  • pyruvate dehydrogenase E1 alpha subunit, mitochondrial precursor
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PROTON[c] + 1 THIAMINE-PYROPHOSPHATE[c] + 1 PYRUVATE[c] => 1 CARBON-DIOXIDE[c] + 1 2-ALPHA-HYDROXYETHYL-THPP[c]
• With common name(s):
  • 1 H+[c] + 1 thiamine diphosphate[c] + 1 pyruvate[c] => 1 CO2[c] + 1 2-(α-hydroxyethyl)thiamine diphosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: CHC_T00008732001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: CHC_T00008732001_1
  • Source: orthology-galdieria.sulphuraria
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-arabidopsis_thaliana
• Gene: CHC_T00008442001_1
  • Source: orthology-galdieria.sulphuraria
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-arabidopsis_thaliana

Reconstruction information

• Category: orthology
  • Source: orthology-galdieria.sulphuraria
    • Tool: pantograph
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-original_genome
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R00014