RXN0-1132

Reaction RXN0-1132

• direction:
  • LEFT-TO-RIGHT
• common name:
  • pyruvate dehydrogenase E1 alpha subunit, mitochondrial precursor
  • dihydrolipoamide dehydrogenase
  • lipoamide dehydrogenase
• ec number:
  • EC-1.8.1.4
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 Pyruvate-dehydrogenase-dihydrolipoate[c] => 1 PROTON[c] + 1 Pyruvate-dehydrogenase-lipoate[c] + 1 NADH[c]
• With common name(s):
  • 1 NAD+[c] + 1 a [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine[c] => 1 H+[c] + 1 a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: CHC_T00008441001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: CHC_T00008441001_1
  • Source: orthology-galdieria.sulphuraria
  • Source: orthology-ectocarpus_siliculosus
• Gene: CHC_T00010287001_1
  • Source: orthology-galdieria.sulphuraria
  • Source: orthology-ectocarpus_siliculosus
• Gene: CHC_T00008732001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: CHC_T00010287001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH

Pathways

• PYRUVDEHYD-PWY, pyruvate decarboxylation to acetyl CoA: PYRUVDEHYD-PWY
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-galdieria.sulphuraria
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-original_genome
    • Tool: pathwaytools