Difference between revisions of "2OXOGLUTDECARB-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=1.1.1.8-RXN 1.1.1.8-RXN] == * direction: ** LEFT-TO-RIGHT * ec number: ** [http://enzyme.expasy.org...")
 
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=1.1.1.8-RXN 1.1.1.8-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=2OXOGLUTDECARB-RXN 2OXOGLUTDECARB-RXN] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 +
* common name:
 +
** dihydrolipoamide dehydrogenase
 +
** 2-oxoglutarate dehydrogenase, E1 component
 
* ec number:
 
* ec number:
** [http://enzyme.expasy.org/EC/1.1.1.8 EC-1.1.1.8]
+
** [http://enzyme.expasy.org/EC/1.2.4.2 EC-1.2.4.2]
 
* Synonym(s):
 
* Synonym(s):
 +
** Oxoglutarate decarboxylase
 +
** 2-oxoglutarate decarboxylation
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 1 [[NADH]][c] '''+''' 1 [[DIHYDROXY-ACETONE-PHOSPHATE]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[NAD]][c] '''+''' 1 [[GLYCEROL-3P]][c]
+
** 1 [[PROTON]][c] '''+''' 1 [[Oxo-glutarate-dehydrogenase-lipoyl]][c] '''+''' 1 [[2-KETOGLUTARATE]][c] '''=>''' 1 [[Oxo-glutarate-dehydro-suc-DH-lipoyl]][c] '''+''' 1 [[CARBON-DIOXIDE]][c]
 
* With common name(s):
 
* With common name(s):
** 1 NADH[c] '''+''' 1 glycerone phosphate[c] '''+''' 1 H+[c] '''=>''' 1 NAD+[c] '''+''' 1 sn-glycerol 3-phosphate[c]
+
** 1 H+[c] '''+''' 1 a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] '''+''' 1 2-oxoglutarate[c] '''=>''' 1 a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine[c] '''+''' 1 CO2[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* [[CHC_T00009494001_1]]
+
* Gene: [[CHC_T00010287001_1]]
** [[pantograph]]-[[galdieria.sulphuraria]]
+
** Source: [[orthology-galdieria.sulphuraria]]
 +
** Source: [[orthology-ectocarpus_siliculosus]]
 +
* Gene: [[CHC_T00008312001]]
 +
** Source: [[annotation-original_genome]]
 +
*** Assignment: AUTOMATED-NAME-MATCH
 +
* Gene: [[CHC_T00008441001]]
 +
** Source: [[annotation-original_genome]]
 +
*** Assignment: AUTOMATED-NAME-MATCH
 +
* Gene: [[CHC_T00008441001_1]]
 +
** Source: [[orthology-galdieria.sulphuraria]]
 +
** Source: [[orthology-ectocarpus_siliculosus]]
 +
* Gene: [[CHC_T00008312001_1]]
 +
** Source: [[orthology-galdieria.sulphuraria]]
 +
** Source: [[orthology-ectocarpus_siliculosus]]
 
== Pathways  ==
 
== Pathways  ==
* [[PWY-6118]], glycerol-3-phosphate shuttle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6118 PWY-6118]
+
* [[PWY66-398]], TCA cycle III (animals): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-398 PWY66-398]
** '''1''' reactions found over '''2''' reactions in the full pathway
+
** '''11''' reactions found over '''11''' reactions in the full pathway
* [[PWY-7411]], phosphatidate biosynthesis (yeast): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7411 PWY-7411]
+
* [[PWY-5084]], 2-oxoglutarate decarboxylation to succinyl-CoA: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5084 PWY-5084]
** '''5''' reactions found over '''5''' reactions in the full pathway
+
** '''3''' reactions found over '''3''' reactions in the full pathway
* [[PWY-7385]], 1,3-propanediol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7385 PWY-7385]
+
** '''5''' reactions found over '''9''' reactions in the full pathway
+
 
== Reconstruction information  ==
 
== Reconstruction information  ==
* [[orthology]]:
+
* Category: [[orthology]]
** [[pantograph]]:
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** Source: [[orthology-galdieria.sulphuraria]]
*** [[galdieria.sulphuraria]]
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*** Tool: [[pantograph]]
* [[annotation]]:
+
** Source: [[orthology-ectocarpus_siliculosus]]
** [[pathwaytools]]:
+
*** Tool: [[pantograph]]
*** [[original_genome]]
+
* Category: [[annotation]]
 +
** Source: [[annotation-original_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
* LIGAND-RXN:
 
** [http://www.genome.jp/dbget-bin/www_bget?R00842 R00842]
 
 
* UNIPROT:
 
* UNIPROT:
** [http://www.uniprot.org/uniprot/P13707 P13707]
+
** [http://www.uniprot.org/uniprot/P23129 P23129]
** [http://www.uniprot.org/uniprot/P08507 P08507]
+
** [http://www.uniprot.org/uniprot/Q02218 Q02218]
** [http://www.uniprot.org/uniprot/O25614 O25614]
+
** [http://www.uniprot.org/uniprot/Q60597 Q60597]
** [http://www.uniprot.org/uniprot/Q9JWH0 Q9JWH0]
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** [http://www.uniprot.org/uniprot/Q9JRJ8 Q9JRJ8]
** [http://www.uniprot.org/uniprot/P43798 P43798]
+
** [http://www.uniprot.org/uniprot/P20967 P20967]
** [http://www.uniprot.org/uniprot/O29390 O29390]
+
** [http://www.uniprot.org/uniprot/P0AFG3 P0AFG3]
** [http://www.uniprot.org/uniprot/P46919 P46919]
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** [http://www.uniprot.org/uniprot/P20707 P20707]
** [http://www.uniprot.org/uniprot/P07735 P07735]
+
** [http://www.uniprot.org/uniprot/P51056 P51056]
** [http://www.uniprot.org/uniprot/P13706 P13706]
+
** [http://www.uniprot.org/uniprot/Q56600 Q56600]
** [http://www.uniprot.org/uniprot/Q00055 Q00055]
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** [http://www.uniprot.org/uniprot/O49541 O49541]
** [http://www.uniprot.org/uniprot/P34517 P34517]
+
** [http://www.uniprot.org/uniprot/Q59106 Q59106]
** [http://www.uniprot.org/uniprot/P0A6S7 P0A6S7]
+
** [http://www.uniprot.org/uniprot/Q9M2T8 Q9M2T8]
** [http://www.uniprot.org/uniprot/P21695 P21695]
+
** [http://www.uniprot.org/uniprot/Q9ZRQ2 Q9ZRQ2]
** [http://www.uniprot.org/uniprot/P41911 P41911]
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** [http://www.uniprot.org/uniprot/P90593 P90593]
+
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
{{#set: ec number=EC-1.1.1.8}}
+
{{#set: common name=dihydrolipoamide dehydrogenase}}
{{#set: gene associated=CHC_T00009494001_1}}
+
{{#set: common name=2-oxoglutarate dehydrogenase, E1 component}}
{{#set: in pathway=PWY-6118|PWY-7411|PWY-7385}}
+
{{#set: ec number=EC-1.2.4.2}}
{{#set: reconstruction category=orthology}}
+
{{#set: common name=Oxoglutarate decarboxylase|2-oxoglutarate decarboxylation}}
{{#set: reconstruction tool=pantograph}}
+
{{#set: gene associated=CHC_T00010287001_1|CHC_T00008312001|CHC_T00008441001|CHC_T00008441001_1|CHC_T00008312001_1}}
{{#set: reconstruction source=galdieria.sulphuraria}}
+
{{#set: in pathway=PWY66-398|PWY-5084}}
{{#set: reconstruction category=annotation}}
+
{{#set: reconstruction category=orthology|annotation}}
{{#set: reconstruction tool=pathwaytools}}
+
{{#set: reconstruction source=orthology-galdieria.sulphuraria|annotation-original_genome|orthology-ectocarpus_siliculosus}}
{{#set: reconstruction source=original_genome}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 17:02, 9 January 2019

Reaction 2OXOGLUTDECARB-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • dihydrolipoamide dehydrogenase
    • 2-oxoglutarate dehydrogenase, E1 component
  • ec number:
  • Synonym(s):
    • Oxoglutarate decarboxylase
    • 2-oxoglutarate decarboxylation

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY66-398, TCA cycle III (animals): PWY66-398
    • 11 reactions found over 11 reactions in the full pathway
  • PWY-5084, 2-oxoglutarate decarboxylation to succinyl-CoA: PWY-5084
    • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

External links