2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN

Reaction RXN66-311

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 4α-hydroxymethyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol dehydrogenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PROTON[c] + 1 OXYGEN-MOLECULE[c] + 1 NADH-P-OR-NOP[c] + 1 CPD-4575[c] => 2 WATER[c] + 1 CPD-4576[c] + 1 NAD-P-OR-NOP[c]
• With common name(s):
  • 1 H+[c] + 1 oxygen[c] + 1 NAD(P)H[c] + 1 4α-hydroxymethyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol[c] => 2 H2O[c] + 1 4α-formyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol[c] + 1 NAD(P)+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• CHC_T00010320001_1
  • pantograph-galdieria.sulphuraria

Pathways

• PWY66-341, cholesterol biosynthesis I: PWY66-341
  • 14 reactions found over 22 reactions in the full pathway
• PWY-6074, zymosterol biosynthesis: PWY-6074
  • 10 reactions found over 12 reactions in the full pathway
• PWY66-4, cholesterol biosynthesis III (via desmosterol): PWY66-4
  • 15 reactions found over 22 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • galdieria.sulphuraria