2.4.1.224-RXN

Reaction 2.4.1.224-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Glycosyltransferase, family GT47
  • Glycosyltransferase, family GT64
  • Glycosyltransferase, family GT49
  • Glycosyltransferase, family GT34
  • Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase, family GT22
  • UDP-glucose:glycoprotein glucosyltransferase, family GT24
  • Beta1,3-galactosyltransferase, family GT31
• ec number:
  • EC-2.4.1.224
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 GlcA-GlcNAc-GlcA-Gal-Gal-Xyl-Protein[c] + 1 UDP-N-ACETYL-D-GLUCOSAMINE[c] => 1 GlcNAc-GlcA-GlcNAc-GlcA-Gal-Gal-Xyl-Core[c] + 1 PROTON[c] + 1 UDP[c]
• With common name(s):
  • 1 β-D-glucosyluronate-(1->3)-α-N-acetyl-D-glucosaminyl-(1->4)-β-D-glucosyluronate-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein][c] + 1 UDP-N-acetyl-α-D-glucosamine[c] => 1 α-N-acetyl-D-glucosaminyl-β-D-glucosyluronate-(1->3)-α-N-acetyl-D-glucosaminyl-(1->4)-β-D-glucosyluronate-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-[core protein][c] + 1 H+[c] + 1 UDP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• EsuBft600_4a
  • GENOME
    • EC-NUMBER
• EsuBft596_5a
  • GENOME
    • EC-NUMBER
• EsuBft812_2a
  • GENOME
    • EC-NUMBER
• EsuBft1580_7a
  • GENOME
    • EC-NUMBER
• EsuBft2107_5a
  • GENOME
    • EC-NUMBER
• EsuBft952_4a
  • GENOME
    • EC-NUMBER
• EsuBft489_8a
  • GENOME
    • EC-NUMBER
• EsuBft1156_5a
  • GENOME
    • EC-NUMBER
• EsuBft812_3a
  • GENOME
    • EC-NUMBER
• EsuBft1354_3a
  • GENOME
    • EC-NUMBER

Pathways

• PWY-6558, heparan sulfate biosynthesis (late stages): PWY-6558
  • 1 reactions found over 13 reactions in the full pathway

Reconstruction information

• annotation:
  • pathwaytools:
    • genome

External links

• LIGAND-RXN:
  • R07334