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	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
2.4.1.229-RXN	EC-2.4.1.229	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 2887
2.4.1.46-RXN	EC-2.4.1.46	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9530 Tiso gene 4096	PWY-401
2.4.1.67-RXN	EC-2.4.1.67	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 8673 Tiso gene 16101	PWY-5337
2.4.1.83-RXN	EC-2.4.1.83	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 16772	MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
2.5.1.32-RXN		Orthology	Pantograph	Orthology-synechocystis Orthology-esiliculosus	Tiso gene 15914	PWY-6287 PWY-6475
2.5.1.58-RXN	EC-2.5.1.58	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 19356
2.5.1.64-RXN	EC-2.2.1.9	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1922 Tiso gene 17551	PWY-5837
2.6.1.7-RXN	EC-2.6.1.7	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 15680	PWY-6309
2.7.1.127-RXN	EC-2.7.1.127	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 15142 Tiso gene 8121 Tiso gene 15143	PWY-6364 PWY-6362 PWY-6361
2.7.1.133-RXN	EC-2.7.1.159	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 15232	PWY-6366 PWY-6365 PWY-6362 PWY-6554
2.7.1.134-RXN	EC-2.7.1.134	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 15232	PWY-6365 PWY-4661
2.7.1.139-RXN	EC-2.7.1.159	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 15232	PWY-6554
2.7.1.148-RXN	EC-2.7.1.148	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 13463	NONMEVIPP-PWY PWY-7560
2.7.1.68-RXN	EC-2.7.1.68	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 9590 Tiso gene 14055 Tiso gene 14966 Tiso gene 2021 Tiso gene 7487 Tiso gene 15721 Tiso gene 1131 Tiso gene 2008 Tiso gene 18887 Tiso gene 17887 Tiso gene 9249 Tiso gene 730 Tiso gene 2350 Tiso gene 15722 Tiso gene 17532 Tiso gene 11381	PWY-6352 PWY-6351
2.7.10.1-RXN	EC-2.7.10.2 EC-2.7.12.1 EC-2.7.10.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 6071 Tiso gene 2393 Tiso gene 14940 Tiso gene 10355 Tiso gene 12229 Tiso gene 14941 Tiso gene 5584 Tiso gene 9800 Tiso gene 17047 Tiso gene 18523 Tiso gene 15652 Tiso gene 1810 Tiso gene 17980 Tiso gene 10356 Tiso gene 1492
2.7.11.2-RXN	EC-2.7.11.2	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 20269 Tiso gene 12579 Tiso gene 20270
2.7.11.22-RXN		Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 19151 Tiso gene 7932
2.7.11.24-RXN	EC-2.7.11.24	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 7161 Tiso gene 15329 Tiso gene 169 Tiso gene 1338 Tiso gene 10060 Tiso gene 2152 Tiso gene 15060 Tiso gene 8480 Tiso gene 9582 Tiso gene 10793 Tiso gene 10792 Tiso gene 19611
2.7.13.3-RXN	EC-2.7.13.3	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 3454 Tiso gene 1942 Tiso gene 20472 Tiso gene 5545
2.7.7.14-RXN	EC-2.7.7.14	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 18070	PWY-7782 PWY4FS-6
2.7.7.60-RXN	EC-2.7.7.60	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 17568	NONMEVIPP-PWY PWY-7560
2.7.7.8-RXN	EC-2.7.7.8	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 2987
2.7.8.11-RXN	EC-2.7.8.11	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 6541	PHOSLIPSYN2-PWY PWY-7625 PWY-6351 PWY-6352
2.7.8.15-RXN	EC-2.7.8.15	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1604	MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
2.7.8.23-RXN	EC-2.7.8.23	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 2241
2.7.9.3-RXN	EC-2.7.9.3	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 5668 Tiso gene 5669 Tiso gene 14608	PWY0-901 PWY-6281
2.8.1.6-RXN	EC-2.8.1.6	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 10345	PWY0-1507 PWY-7380
2PGADEHYDRAT-RXN	EC-4.2.1.11	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 5619 Tiso gene 13317 Tiso gene 14718 Tiso gene 8720	PWY-1042 P341-PWY PWY-2221 PWY-7124 PWY-1622 GLUCONEO-PWY GLYCOLYSIS NPGLUCAT-PWY ANAGLYCOLYSIS-PWY PWY-7218 PWY-6901 P124-PWY PWY-6886 PWY-5723 PWY-6142 P122-PWY PWY66-399 PWY-5484 PWY-7003
3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN	EC-2.1.2.11	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 14465 Tiso gene 14466	PANTO-PWY
3-DEHYDROQUINATE-DEHYDRATASE-RXN	EC-4.2.1.10	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 5619 Tiso gene 14718 Tiso gene 8720 Tiso gene 5753 Tiso gene 5752	PWY-6163 PWY-6416 QUINATEDEG-PWY PWY-6707
3-DEHYDROQUINATE-SYNTHASE-RXN	EC-4.2.3.4	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 5753 Tiso gene 3446 Tiso gene 3445 Tiso gene 3974 Tiso gene 5752 Tiso gene 3447	PWY-6164
3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN	EC-1.1.1.157	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 14026 Tiso gene 14027
3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN	EC-1.1.1.31	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus Annotation-experimental annotation	Tiso gene 19590 Tiso gene 5857 Tiso gene 19771 Tiso gene 7107 Tiso gene 19772 Tiso gene 19592	VALDEG-PWY
3-ISOPROPYLMALDEHYDROG-RXN		Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-experimental annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 2920	LEUSYN-PWY PWY-6871
3-ISOPROPYLMALISOM-RXN		Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 12778	LEUSYN-PWY PWY-6871
3-OXOACYL-ACP-REDUCT-RXN	EC-2.3.1.86 EC-2.3.1.85 EC-1.1.1.100	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 10876 Tiso gene 13394 Tiso gene 9885 Tiso gene 135 Tiso gene 13083 Tiso gene 136 Tiso gene 500	FASYN-ELONG-PWY
3-OXOACYL-ACP-SYNTH-BASE-RXN	EC-2.3.1.86 EC-2.3.1.85 EC-2.3.1.41	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 19302 Tiso gene 136 Tiso gene 14485 Tiso gene 13394 Tiso gene 5939 Tiso gene 135 Tiso gene 10876 Tiso gene 500 Tiso gene 15991	PWY-5965 PWY-5966 FASYN-INITIAL-PWY PWY-7388
3-OXOACYL-ACP-SYNTH-RXN	EC-2.3.1.86 EC-2.3.1.85 EC-2.3.1.41	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 136 Tiso gene 15991 Tiso gene 14485 Tiso gene 135 Tiso gene 13394 Tiso gene 500 Tiso gene 5939 Tiso gene 10876 Tiso gene 19302	FASYN-ELONG-PWY
3-SULFINOALANINE-AMINOTRANSFERASE-RXN	EC-2.6.1	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 17718	CYSTEINE-DEG-PWY
3.1.1.64-RXN	EC-3.1.1.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1538 Tiso gene 1537 Tiso gene 9429 Tiso gene 1922 Tiso gene 2556 Tiso gene 19778 Tiso gene 12686 Tiso gene 4606 Tiso gene 4650 Tiso gene 10066 Tiso gene 17029 Tiso gene 16518 Tiso gene 11351
3.1.26.4-RXN	EC-3.1.26.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9453 Tiso gene 3410 Tiso gene 9459 Tiso gene 16584 Tiso gene 10743
3.1.26.5-RXN	EC-3.1.26.5	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 14345 Tiso gene 14344 Tiso gene 10972 Tiso gene 3898 Tiso gene 10971	PWY0-1479
3.1.27.1-RXN	EC-3.1.27.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 11979 Tiso gene 13100 Tiso gene 8896
3.1.3.16-RXN	EC-3.1.3.16	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 452 Tiso gene 2190 Tiso gene 7036 Tiso gene 3751 Tiso gene 15176 Tiso gene 17314 Tiso gene 5305 Tiso gene 1395 Tiso gene 10912 Tiso gene 7035 Tiso gene 2578 Tiso gene 15559 Tiso gene 13371 Tiso gene 18472 Tiso gene 19603 Tiso gene 16524 Tiso gene 15788 Tiso gene 16525 Tiso gene 20309 Tiso gene 4137 Tiso gene 12379 Tiso gene 4164 Tiso gene 2034 Tiso gene 11870 Tiso gene 453 Tiso gene 18502 Tiso gene 12989 Tiso gene 1840
3.1.3.67-RXN	EC-3.1.3.67	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 19083	PWY-6368
3.1.4.11-RXN	EC-3.1.4.11	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 7561 Tiso gene 12020 Tiso gene 12019	PWY-6367 PWY-6351 PWY-7039 LIPASYN-PWY
3.1.4.17-RXN	EC-3.1.4.17	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9644 Tiso gene 1763 Tiso gene 12792
3.2.1.106-RXN	EC-3.2.1.106	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 12662
3.2.1.113-RXN	EC-3.2.1.113	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 4788 Tiso gene 11681 Tiso gene 2719
3.2.1.21-RXN	EC-3.2.1.21	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 6187 Tiso gene 15066 Tiso gene 3467 Tiso gene 8669 Tiso gene 5836 Tiso gene 6188 Tiso gene 2843 Tiso gene 15067 Tiso gene 6497 Tiso gene 13305 Tiso gene 13306 Tiso gene 6007 Tiso gene 10001 Tiso gene 2344

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