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	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
2.4.1.232-RXN	EC-2.4.1.232	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10734 Tiso gene 16872
2.4.1.32-RXN	EC-2.4.1.32	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 322
2.4.1.46-RXN	EC-2.4.1.46	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9530 Tiso gene 4096	PWY-401
2.4.1.83-RXN	EC-2.4.1.83	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 16772	MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
2.4.2.12-RXN	EC-2.4.2.12	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation	Tiso gene 8411 Tiso gene 8186 Tiso gene 8410	NAD-BIOSYNTHESIS-III
2.4.2.31-RXN	EC-2.4.2.31	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 1416 Tiso gene 16539 Tiso gene 17880 Tiso gene 18844 Tiso gene 19256 Tiso gene 16775 Tiso gene 17938 Tiso gene 14179 Tiso gene 16690 Tiso gene 8768 Tiso gene 19047 Tiso gene 16538 Tiso gene 13548 Tiso gene 18843 Tiso gene 5361 Tiso gene 1521
2.5.1.19-RXN	EC-2.5.1.19	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Manual-primary network Annotation-in-silico annotation Orthology-athaliana	Tiso gene 5752 Tiso gene 5753	PWY-6163
2.5.1.64-RXN	EC-2.2.1.9	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1922 Tiso gene 17551	PWY-5837
2.6.1.22-RXN	EC-2.6.1.22	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation		VALDEG-PWY
2.7.1.127-RXN	EC-2.7.1.127	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 15142 Tiso gene 8121 Tiso gene 15143	PWY-6364 PWY-6362 PWY-6361
2.7.1.133-RXN	EC-2.7.1.159	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 15232	PWY-6366 PWY-6365 PWY-6362 PWY-6554
2.7.1.134-RXN	EC-2.7.1.134	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 15232	PWY-6365 PWY-4661
2.7.1.139-RXN	EC-2.7.1.159	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 15232	PWY-6554
2.7.1.140-RXN	EC-2.7.1.140	Annotation	Pathwaytools	Annotation-in-silico annotation		PWY-6366 PWY-6372 PWY-6365 PWY-6362 PWY-6554
2.7.1.148-RXN	EC-2.7.1.148	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 13463	NONMEVIPP-PWY PWY-7560
2.7.1.149-RXN	EC-2.7.1.149	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation		PWY-6367 PWY-6351
2.7.1.160-RXN	EC-2.7.1.160	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 17372	PWY-6689
2.7.1.68-RXN	EC-2.7.1.68	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 9590 Tiso gene 14055 Tiso gene 14966 Tiso gene 2021 Tiso gene 7487 Tiso gene 15721 Tiso gene 1131 Tiso gene 2008 Tiso gene 18887 Tiso gene 17887 Tiso gene 9249 Tiso gene 730 Tiso gene 2350 Tiso gene 15722 Tiso gene 17532 Tiso gene 11381	PWY-6352 PWY-6351
2.7.1.90-RXN	EC-2.7.1.90	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation	Tiso gene 596	PWY-1042
2.7.10.1-RXN	EC-2.7.10.2 EC-2.7.12.1 EC-2.7.10.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 6071 Tiso gene 2393 Tiso gene 14940 Tiso gene 10355 Tiso gene 12229 Tiso gene 14941 Tiso gene 5584 Tiso gene 9800 Tiso gene 17047 Tiso gene 18523 Tiso gene 15652 Tiso gene 1810 Tiso gene 17980 Tiso gene 10356 Tiso gene 1492
2.7.11.18-RXN	EC-2.7.11.18	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation	Tiso gene 4338 Tiso gene 4337 Tiso gene 6216
2.7.11.2-RXN	EC-2.7.11.2	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 20269 Tiso gene 12579 Tiso gene 20270
2.7.11.20-RXN	EC-2.7.11.20	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 15126
2.7.11.24-RXN	EC-2.7.11.24	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 7161 Tiso gene 15329 Tiso gene 169 Tiso gene 1338 Tiso gene 10060 Tiso gene 2152 Tiso gene 15060 Tiso gene 8480 Tiso gene 9582 Tiso gene 10793 Tiso gene 10792 Tiso gene 19611
2.7.12.1-RXN	EC-2.7.11.11 EC-2.7.12.1	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 1810
2.7.12.2-RXN	EC-2.7.12.2	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 18334
2.7.7.11-RXN	EC-2.7.7.11	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6457 Tiso gene 6459 Tiso gene 6458
2.7.7.14-RXN	EC-2.7.7.14	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 18070	PWY-7782 PWY4FS-6
2.7.7.44-RXN	EC-2.7.7.44	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6458 Tiso gene 6459 Tiso gene 6457	PWY-4841
2.7.7.60-RXN	EC-2.7.7.60	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 17568	NONMEVIPP-PWY PWY-7560
2.7.7.8-RXN	EC-2.7.7.8	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 2987
2.7.8.11-RXN	EC-2.7.8.11	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 6541	PHOSLIPSYN2-PWY PWY-7625 PWY-6351 PWY-6352
2.7.8.15-RXN	EC-2.7.8.15	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1604	MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
2.7.9.3-RXN	EC-2.7.9.3	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 5668 Tiso gene 5669 Tiso gene 14608	PWY0-901 PWY-6281
2.8.1.6-RXN	EC-2.8.1.6	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 10345	PWY0-1507 PWY-7380
2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN	EC-1.2.1	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation		LEU-DEG2-PWY
2OXOGLUTDECARB-RXN	EC-1.2.4.2	Manual Annotation	Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation	Tiso gene 10209	PWY66-398 PWY-5084
2PGADEHYDRAT-RXN	EC-4.2.1.11	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 5619 Tiso gene 13317 Tiso gene 14718 Tiso gene 8720	PWY-1042 P341-PWY PWY-2221 PWY-7124 PWY-1622 GLUCONEO-PWY GLYCOLYSIS NPGLUCAT-PWY ANAGLYCOLYSIS-PWY PWY-7218 PWY-6901 P124-PWY PWY-6886 PWY-5723 PWY-6142 P122-PWY PWY66-399 PWY-5484 PWY-7003
2TRANSKETO-RXN	EC-2.2.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Manual-primary network	Tiso gene 11559 Tiso gene 5008	PWY-6901 CALVIN-PWY P21-PWY PWY-5723 PWY-1861 P185-PWY NONOXIPENT-PWY
3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN	EC-2.1.2.11	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 14465 Tiso gene 14466	PANTO-PWY
3-DEHYDROQUINATE-DEHYDRATASE-RXN	EC-4.2.1.10	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 5619 Tiso gene 14718 Tiso gene 8720 Tiso gene 5753 Tiso gene 5752	PWY-6163 PWY-6416 QUINATEDEG-PWY PWY-6707
3-DEHYDROQUINATE-SYNTHASE-RXN	EC-4.2.3.4	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 5753 Tiso gene 3446 Tiso gene 3445 Tiso gene 3974 Tiso gene 5752 Tiso gene 3447	PWY-6164
3-DEHYDROSPHINGANINE-REDUCTASE-RXN	EC-1.1.1.102	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation	Tiso gene 18518	PWY-5129 PWY3DJ-12 SPHINGOLIPID-SYN-PWY
3-HYDROXY-KYNURENINASE-RXN	EC-3.7.1.3	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10684 Tiso gene 10685	PWY-5651 PWY-6309
3-HYDROXYDECANOYL-ACP-DEHYDR-RXN	EC-2.3.1.86 EC-2.3.1.85 EC-4.2.1.59	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 136 Tiso gene 500 Tiso gene 6884 Tiso gene 135 Tiso gene 10876 Tiso gene 13394	FASYN-ELONG-PWY
3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN	EC-1.1.1.31	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus Annotation-experimental annotation	Tiso gene 19590 Tiso gene 5857 Tiso gene 19771 Tiso gene 7107 Tiso gene 19772 Tiso gene 19592	VALDEG-PWY
3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN	EC-3.1.2.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-creinhardtii Annotation-experimental annotation	Tiso gene 2224	VALDEG-PWY
3-ISOPROPYLMALDEHYDROG-RXN		Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-experimental annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 2920	LEUSYN-PWY PWY-6871
3-ISOPROPYLMALISOM-RXN		Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 12778	LEUSYN-PWY PWY-6871
3-OXOACID-COA-TRANSFERASE-RXN	EC-2.8.3.5	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 6754

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