2OXOGLUTDECARB-RXN

Reaction 2OXOGLUTDECARB-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • oxoglutarate dehydrogenase (succinyl-transferring)
  • ORF
• ec number:
  • EC-1.2.4.2
• Synonym(s):
  • Oxoglutarate decarboxylase
  • 2-oxoglutarate decarboxylation

Reaction Formula

• With identifiers:
  • 1 Oxo-glutarate-dehydrogenase-lipoyl[c] + 1 PROTON[c] + 1 2-KETOGLUTARATE[c] => 1 Oxo-glutarate-dehydro-suc-DH-lipoyl[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] + 1 H+[c] + 1 2-oxoglutarate[c] => 1 a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• EsuBft779_3a
  • GENOME
    • EC-NUMBER
• EsuBft683_9a
  • GENOME
    • EC-NUMBER
• EsuBft779_4a
  • GENOME
    • GO-TERM

Pathways

• PWY-5084, 2-oxoglutarate decarboxylation to succinyl-CoA: PWY-5084
  • 3 reactions found over 3 reactions in the full pathway
• PWY66-398, TCA cycle III (animals): PWY66-398
  • 10 reactions found over 11 reactions in the full pathway

Reconstruction information

• annotation:
  • pathwaytools:
    • genome

External links

• UNIPROT:
  • P23129
  • Q02218
  • Q60597
  • Q9JRJ8
  • P20967
  • P0AFG3
  • P20707
  • P51056
  • Q56600
  • O49541
  • Q59106
  • Q9M2T8
  • Q9ZRQ2